Oxidative stress and alterations in DNA methylation: two sides of the same coin in reproduction

YJR Menezo, E Silvestris, B Dale, K Elder - Reproductive biomedicine …, 2016 - Elsevier
The negative effect of oxidative stress on the human reproductive process is no longer a
matter for debate. Oxidative stress affects female and male gametes and the developmental …

Regulation of mammalian gene expression by retroelements and non‐coding tandem repeats

NV Tomilin - Bioessays, 2008 - Wiley Online Library
Genomes of higher eukaryotes contain abundant non‐coding repeated sequences whose
overall biological impact is unclear. They comprise two categories. The first consists of …

[HTML][HTML] S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon …

J Luo, YN Li, F Wang, WM Zhang… - International journal of …, 2010 - ncbi.nlm.nih.gov
A global DNA hypomethylation might activate oncogene transcription, thus promoting
carcinogenesis and tumor development. S-Adenosylmethionine (SAM) serves as a major …

DNA methylation and body temperature in fishes

A Varriale, G Bernardi - Gene, 2006 - Elsevier
Previous investigations from our laboratory [Jabbari, K., Cacciò, S., Pais de Barros, JP,
Desgres, J., Bernardi G., 1997. Evolutionary changes in CpG and methylation levels in the …

Unique ERα cistromes control cell type-specific gene regulation

SA Krum, GA Miranda-Carboni, M Lupien… - Molecular …, 2008 - academic.oup.com
Estrogens play an important role in normal physiology and in a variety of pathological states
involving diverse tissues including breast and bone. The mechanism by which estrogens …

[HTML][HTML] Undetectable levels of N6-methyl adenine in mouse DNA: cloning and analysis of PRED28, a gene coding for a putative mammalian DNA adenine …

D Ratel, JL Ravanat, MP Charles, N Platet, L Breuillaud… - FEBS letters, 2006 - Elsevier
Three methylated bases, 5-methylcytosine, N4-methylcytosine and N6-methyladenine
(m6A), can be found in DNA. However, to date, only 5-methylcytosine has been detected in …

[HTML][HTML] Analysis of DNA methylation in various swine tissues

C Yang, M Zhang, W Niu, R Yang, Y Zhang, Z Qiu… - Plos one, 2011 - journals.plos.org
DNA methylation is known to play an important role in regulating gene expression during
biological development and tissue differentiation in eukaryotes. In this study, we used the …

Exocyclic Carbons Adjacent to the N6 of Adenine are Targets for Oxidation by the Escherichia coli Adaptive Response Protein AlkB

D Li, JC Delaney, CM Page, X Yang… - Journal of the …, 2012 - ACS Publications
The DNA and RNA repair protein AlkB removes alkyl groups from nucleic acids by a unique
iron-and α-ketoglutarate-dependent oxidation strategy. When alkylated adenines are used …

Conformation-selective methylation of geminivirus DNA

T Paprotka, K Deuschle, V Metzler, H Jeske - Journal of virology, 2011 - Am Soc Microbiol
Geminiviruses with small circular single-stranded DNA genomes replicate in plant cell nuclei
by using various double-stranded DNA (dsDNA) intermediates: distinct open circular and …

5-Azacytidine treatment and TaPBF-D over-expression increases glutenin accumulation within the wheat grain by hypomethylating the Glu-1 promoters

J Zhu, L Fang, J Yu, Y Zhao, F Chen, G Xia - Theoretical and Applied …, 2018 - Springer
Key message 5-azaC treatment and TaPBF-D over-expression decrease C-methylation
status of three Glu-1 gene promoters, and aid in enhancing the expression of the Glu-1 …