The application of computational modeling for risk prediction in type B aortic dissection

B Munshi, LP Parker, PE Norman, BJ Doyle - Journal of vascular surgery, 2020 - Elsevier
Objective New tools are urgently needed to help with surgical decision-making in type B
aortic dissection (TBAD) that is uncomplicated at the time of initial presentation. This …

Computational biomechanics in thoracic aortic dissection: today's approaches and tomorrow's opportunities

BJ Doyle, PE Norman - Annals of biomedical engineering, 2016 - Springer
Dissection of an artery is characterised by the separation of the layers of the arterial wall
causing blood to flow within the wall. The incidence rates of thoracic aortic dissection (AoD) …

Aortic dissection simulation models for clinical support: fluid-structure interaction vs. rigid wall models

M Alimohammadi, JM Sherwood, M Karimpour… - Biomedical engineering …, 2015 - Springer
Background The management and prognosis of aortic dissection (AD) is often challenging
and the use of personalised computational models is being explored as a tool to improve …

Multi-modality image-based computational analysis of haemodynamics in aortic dissection

D Dillon-Murphy, A Noorani, D Nordsletten… - … and modeling in …, 2016 - Springer
Aortic dissection is a disease whereby an injury in the wall of the aorta leads to the creation
of a true lumen and a false lumen separated by an intimal flap which may contain multiple …

Analysis of flow patterns in a patient-specific aortic dissection model

Z Cheng, FPP Tan, CV Riga, CD Bicknell… - 2010 - asmedigitalcollection.asme.org
Aortic dissection is the most common acute catastrophic event affecting the thoracic aorta.
The majority of patients presenting with an uncomplicated type B dissection are treated …

Development of a patient-specific simulation tool to analyse aortic dissections: assessment of mixed patient-specific flow and pressure boundary conditions

M Alimohammadi, O Agu, S Balabani… - Medical engineering & …, 2014 - Elsevier
Aortic dissection has high morbidity and mortality rates and guidelines regarding surgical
intervention are not clearly defined. The treatment of aortic dissection varies with each …

Presence of left atrial fibrosis may contribute to aberrant hemodynamics and increased risk of stroke in atrial fibrillation patients

N Paliwal, RL Ali, M Salvador, R O'Hara, R Yu… - Frontiers in …, 2021 - frontiersin.org
Atrial fibrillation (AF) patients are at high risk of stroke, with the left atrial appendage (LAA)
found to be the most common site of clot formation. Presence of left atrial (LA) fibrosis has …

[HTML][HTML] Computational study of haemodynamic effects of entry-and exit-tear coverage in a DeBakey type III aortic dissection: technical report

C Karmonik, J Bismuth, DJ Shah, MG Davies… - European journal of …, 2011 - Elsevier
OBJECTIVES: Outcome prediction in DeBakey Type III aortic dissections (ADs) remains
challenging. Large variations in AD morphology, physiology and treatment exist. Here, we …

Hemodynamic analysis in an idealized artery tree: differences in wall shear stress between Newtonian and non-Newtonian blood models

JC Weddell, JH Kwack, PI Imoukhuede, A Masud - PloS one, 2015 - journals.plos.org
Development of many conditions and disorders, such as atherosclerosis and stroke, are
dependent upon hemodynamic forces. To accurately predict and prevent these conditions …

Influence of LVAD cannula outflow tract location on hemodynamics in the ascending aorta: a patient-specific computational fluid dynamics approach

C Karmonik, S Partovi, M Loebe, B Schmack… - Asaio …, 2012 - journals.lww.com
To develop a better understanding of the hemodynamic alterations in the ascending aorta,
induced by variation of the cannula outflow position of the left ventricular assist device …