Highs and lows of hyperoxia: physiological, performance, and clinical aspects
Molecular oxygen (O2) is a vital element in human survival and plays a major role in a
diverse range of biological and physiological processes. Although normobaric hyperoxia …
diverse range of biological and physiological processes. Although normobaric hyperoxia …
Variability of physiological brain perfusion in healthy subjects–A systematic review of modifiers. Considerations for multi-center ASL studies
Quantitative measurements of brain perfusion are influenced by perfusion-modifiers.
Standardization of measurement conditions and correction for important modifiers is …
Standardization of measurement conditions and correction for important modifiers is …
Cerebrovascular and blood–brain barrier impairments in Huntington's disease: potential implications for its pathophysiology
Objective Although the underlying cause of Huntington's disease (HD) is well established,
the actual pathophysiological processes involved remain to be fully elucidated. In other …
the actual pathophysiological processes involved remain to be fully elucidated. In other …
[HTML][HTML] Vascular physiology drives functional brain networks
MG Bright, JR Whittaker, ID Driver, K Murphy - NeuroImage, 2020 - Elsevier
We present the first evidence for vascular regulation driving fMRI signals in specific
functional brain networks. Using concurrent neuronal and vascular stimuli, we collected 30 …
functional brain networks. Using concurrent neuronal and vascular stimuli, we collected 30 …
Multiparametric measurement of cerebral physiology using calibrated fMRI
The ultimate goal of calibrated fMRI is the quantitative imaging of oxygen metabolism
(CMRO 2), and this has been the focus of numerous methods and approaches. However …
(CMRO 2), and this has been the focus of numerous methods and approaches. However …
Searching for a truly “iso-metabolic” gas challenge in physiological MRI
Hypercapnia challenge (eg inhalation of CO2) has been used in calibrated fMRI as well as
in the mapping of vascular reactivity in cerebrovascular diseases. An important assumption …
in the mapping of vascular reactivity in cerebrovascular diseases. An important assumption …
[HTML][HTML] Sources of systematic error in calibrated BOLD based mapping of baseline oxygen extraction fraction
Recently a new class of calibrated blood oxygen level dependent (BOLD) functional
magnetic resonance imaging (MRI) methods were introduced to quantitatively measure the …
magnetic resonance imaging (MRI) methods were introduced to quantitatively measure the …
Meta‐analytic evidence for downregulation of the amygdala during working memory maintenance
LD de Voogd, EJ Hermans - Human Brain Mapping, 2022 - Wiley Online Library
The amygdala is a region critically implicated in affective processes. Downregulation of the
amygdala is one of the hallmarks of successful emotion regulation. Top‐down inhibition of …
amygdala is one of the hallmarks of successful emotion regulation. Top‐down inhibition of …
Gas-free calibrated fMRI with a correction for vessel-size sensitivity
Calibrated functional magnetic resonance imaging (fMRI) is a method to independently
measure the metabolic and hemodynamic contributions to the blood oxygenation level …
measure the metabolic and hemodynamic contributions to the blood oxygenation level …
The impact of hyperoxia on brain activity: A resting-state and task-evoked electroencephalography (EEG) study
A better understanding of the effect of oxygen on brain electrophysiological activity may
provide a more mechanistic insight into clinical studies that use oxygen treatment in …
provide a more mechanistic insight into clinical studies that use oxygen treatment in …