Although recent years have seen large decreases in the overall global rate of suicide
fatalities, this trend is not reflected everywhere. Suicide and suicidal behaviour continue to …

Suicide and self-harm are major health and societal issues worldwide, but the greatest
burden of both behaviours occurs in low-income and middle-income countries. Although …

Suicide is a major public health concern accounting for 800 000 deaths globally each year.
Although there have been many advances in understanding suicide risk in recent decades …

Suicide is a complex public health problem of global importance. Suicidal behaviour differs
between sexes, age groups, geographic regions, and sociopolitical settings, and variably …

Vulnerability to emotional disorders including depression derives from interactions between
genes and environment, especially during sensitive developmental periods. Adverse early …

Importance Observational studies highlight associations of C-reactive protein (CRP), a
general marker of inflammation, and interleukin 6 (IL-6), a cytokine-stimulating CRP …

Suicide continues to be one of the greatest challenges faced by mental health clinicians and
researchers, an issue made worse by increasing trends in the global suicide rate. Suicide …

To identify pan-ancestry and ancestry-specific loci associated with attempting suicide among
veterans, we conducted a genome-wide association study (GWAS) of suicide attempts within …

Neurological illnesses, including cognitive impairment, memory decline and dementia, affect
over 50 million people worldwide, imposing a substantial burden on individuals and society …

Suicide is the second leading cause of death worldwide for adolescents. Despite decades of
research on correlates and risk factors for adolescent suicide, we know little about why …