Hemolytic uremic syndrome (HUS) is characterized by microangiopathic hemolytic anemia,
thrombocytopenia, and renal impairment. Approximately 10% of cases are classified as …

Membranous nephropathy (MN) is defined as disease entity characterized by thickening of
the glomerular basement membranes due to subepithelial (SE) deposition of immune …

Membranoproliferative glomerulonephritis (MPGN) is subdivided into immune-complex-
mediated glomerulonephritis (IC-MPGN) and C3 glomerulopathy (C3G). Classically, MPGN …

Hepatitis C infection and chronic kidney disease are major health burden worldwide.
Hepatitis C infection is associated with a wide range of extra-hepatic manifestations in …

Chronic kidney disease (CKD) has received increased attention as a global health problem
because of its increasing incidence and prevalence, poor outcome and high associated …

Membranoproliferative glomerulonephritis (MPGN) is a pattern of glomerular injury that may
be primary or secondary to infections, autoimmune diseases and haematological disorders …

Biological therapeutics (biologics) that target autoimmune responses and inflammatory
injury pathways have a marked beneficial impact on the management of many chronic …

Background: Genetic defects in complement proteins reportedly contribute to the atypical
hemolytic uremic syndrome (aHUS). Numerous genetic studies have been published in …

The reclassification of membranoproliferative glomerulonephritis (MPGN) into immune-
complex MPGN (IC-MPGN) and C3 glomerulopathy (C3G) based on immunofluorescence …

Background Nephrotic syndrome (NS) is a disorder of the kidney that is defined by the
presence of greater than 3 to 3.5 g per day of proteinuria, which results in hypoalbuminemia …