Background Hemolytic uremic syndrome (HUS) is a leading cause of acute kidney injury in
children. Although international guidelines emphasize comprehensive evaluation and …

Results All patients presented with hematuria, associated with chronic renal failure and
proteinuria in five patients, three of whom had nephrotic syndrome. Five patients had …

The HELLP syndrome, defined by the existence of h emolysis, e levated l iver enzymes, and
l ow p latelet count, is a serious complication of pregnancy-related hypertensive disorders …

Regulators of complement activation (RCA) inhibit complement‐induced immune responses
on healthy host tissues. We present crystal structures of human RCA (MCP, DAF, and CR 1) …

The haemolytic uraemic syndrome (HUS) is characterized by the triad of thrombocytopenia,
microangiopathic haemolytic anaemia and acute renal failure. HUS may be classified as …

El síndrome hemolítico urémico (SHU) es una entidad clínica definida por la tríada anemia
hemolítica no inmune, trombocitopenia e insuficiencia renal aguda, en la que las lesiones …

Renal toxicity constitutes a dose-limiting side effect of anticancer therapies targeting
vascular endothelial growth factor (VEGF). In order to study this further, we followed up 29 …

About 60% of non‐Stx‐associated aHUS are due to the defect of protection of endothelial
cells from complement activation, secondary to mutations in the genes of CFH, MCP, IF, BF …

Platelets have a central function in repairing vascular damage and stopping acute blood
loss. They are equally central to thrombus formation in cardiovascular diseases such as …

Both atypical haemolytic uraemic syndrome (aHUS) and the HELLP syndrome (haemolytic
anaemia, elevated liver enzymes, and low platelets) are thrombotic microangiopathies …