[HTML][HTML] Dynamic regulation of DNA methylation and brain functions

J Xie, L Xie, H Wei, XJ Li, L Lin - Biology, 2023 - mdpi.com
Simple Summary DNA methylation is involved in biological processes including
neurogenesis, aging, and the pathogenesis of brain disorders by the regulation of gene …

Mechanisms of human DNA methylation, alteration of methylation patterns in physiological processes and oncology

A Sergeeva, K Davydova, A Perenkov, M Vedunova - Gene, 2023 - Elsevier
DNA methylation is one of the epigenetic modifications of the genome, the essence of which
is the attachment of a methyl group to nitrogenous bases. In the eukaryote genome, cytosine …

[HTML][HTML] The inactive X chromosome accumulates widespread epigenetic variability with age

Y Liu, L Sinke, TH Jonkman, RC Slieker… - Clinical …, 2023 - Springer
Background Loss of epigenetic control is a hallmark of aging. Among the most prominent
roles of epigenetic mechanisms is the inactivation of one of two copies of the X chromosome …

Epigenetic reprogramming during the maternal‐to‐zygotic transition

Y Chen, L Wang, F Guo, X Dai, X Zhang - MedComm, 2023 - Wiley Online Library
After fertilization, sperm and oocyte fused and gave rise to a zygote which is the beginning of
a new life. Then the embryonic development is monitored and regulated precisely from the …

[HTML][HTML] Epigenomic insights into common human disease pathology

CG Bell - Cellular and Molecular Life Sciences, 2024 - Springer
The epigenome—the chemical modifications and chromatin-related packaging of the
genome—enables the same genetic template to be activated or repressed in different …

Unveiling the exceptional evolution of solute aggregates: From micro to trace, solution to interface

W Wang, H Ma, Q Huang, S Luo, B Ren, Z Tian… - …, 2024 - Wiley Online Library
Existential state of solutes substantially affects the efficiency and direction of various
chemical and biological processes, about which current consensus is still limited at macro …

Probabilistic inference of epigenetic age acceleration from cellular dynamics

JK Dabrowski, EJ Yang, SJC Crofts, RF Hillary… - BioRxiv, 2023 - biorxiv.org
The emergence of epigenetic predictors was a pivotal moment in geroscience, propelling
the measurement and concept of biological ageing into a quantitative era. However, while …

A Comprehensive Review of Various Therapeutic Strategies for the Management of Skin Cancer

SR Dachani, M Kaleem, MA Mujtaba, N Mahajan… - ACS …, 2024 - ACS Publications
Skin cancer (SC) poses a global threat to the healthcare system and is expected to increase
significantly over the next two decades if not diagnosed at an early stage. Early diagnosis is …

Targeting epigenetic age to prevent cancer

M Winnefeld, F Lyko - Nature Reviews Bioengineering, 2023 - nature.com
Targeting epigenetic age to prevent cancer | Nature Reviews Bioengineering Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

UHRF1 ubiquitin ligase activity supports the maintenance of low-density CpG methylation

R Tiedemann, J Hrit, Q Du, AK Wiseman, HE Eden… - bioRxiv, 2024 - biorxiv.org
The RING E3 ubiquitin ligase UHRF1 is an established cofactor for DNA methylation
inheritance. Nucleosomal engagement through histone and DNA interactions directs …