Growth hormone (GH) and prolactin (PRL) are both endocrines that are synthesized and
released from the pituitary gland into systemic circulation. Both are therefore hormones and …

Endometrial receptivity and embryo implantation processes are a major point of pregnancy
failure in many mammalian species, including humans. Although reproductive biology in …

The decidua is a hallmark of reproduction in many placental mammals. Differentiation of
decidual stromal cells is known to be induced by progesterone and the cyclic AMP/protein …

Canine pregnancy relies on luteal steroidogenesis for progesterone (P4) production. The
canine placenta responds to P4, depending on the nuclear P4 receptor (PGR). This has …

Voltage-gated calcium channels and estrogen receptors are essential players in uterine
physiology, and their association with different calcium signaling pathways contributes to …

Among domestic animal species, the reproductive biology of the dog belongs to the most
peculiar. This includes the conceptus-maternal communication and endocrine mechanisms …

Maternal-stroma derived decidual cells, the only cell population in the canine placenta
expressing the nuclear progesterone (P4) receptor (PGR), are crucial for the maintenance of …

In the domestic dog, placentation arises from central implantation, passing through a
transitional, yet important stage of choriovitelline placenta (yolk sac placenta), on the way to …

To date, the biological functions of P4 within the canine placenta have been attributed to
maternal stroma-derived decidual cells as the only placental cells expressing the nuclear P4 …

Contents Leptin (Lep) and insulin‐like growth factor 1 (IGF 1) are implicated in the regulation
of testicular function, but in dogs, our knowledge is limited to the possible role of the IGF 1 …