[HTML][HTML] Epigenome-wide association studies: current knowledge, strategies and recommendations
The aetiology and pathophysiology of complex diseases are driven by the interaction
between genetic and environmental factors. The variability in risk and outcomes in these …
between genetic and environmental factors. The variability in risk and outcomes in these …
Decoding the genetic and epigenetic basis of asthma
Asthma is a complex and heterogeneous chronic inflammatory disease of the airways.
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Alongside environmental factors, asthma susceptibility is strongly influenced by genetics …
Database resources of the national genomics data center, China national center for bioinformation in 2022
Nucleic Acids Research, 2022 - academic.oup.com
Abstract The National Genomics Data Center (NGDC), part of the China National Center for
Bioinformation (CNCB), provides a family of database resources to support global research …
Bioinformation (CNCB), provides a family of database resources to support global research …
Database resources of the national genomics data center, China national center for bioinformation in 2023
Nucleic acids research, 2023 - academic.oup.com
Abstract The National Genomics Data Center (NGDC), part of the China National Center for
Bioinformation (CNCB), provides a family of database resources to support global academic …
Bioinformation (CNCB), provides a family of database resources to support global academic …
[HTML][HTML] The EWAS Catalog: a database of epigenome-wide association studies
Epigenome-wide association studies (EWAS) seek to quantify associations between
traits/exposures and DNA methylation measured at thousands or millions of CpG sites …
traits/exposures and DNA methylation measured at thousands or millions of CpG sites …
Database resources of the national genomics data center in 2020
Nucleic acids research, 2020 - academic.oup.com
Abstract The National Genomics Data Center (NGDC) provides a suite of database
resources to support worldwide research activities in both academia and industry. With the …
resources to support worldwide research activities in both academia and industry. With the …
EWAS Open Platform: integrated data, knowledge and toolkit for epigenome-wide association study
Abstract Epigenome-Wide Association Study (EWAS) has become a standard strategy to
discover DNA methylation variation of different phenotypes. Since 2018, we have developed …
discover DNA methylation variation of different phenotypes. Since 2018, we have developed …
[HTML][HTML] Multi-omics signatures of the human early life exposome
L Maitre, M Bustamante, C Hernández-Ferrer… - Nature …, 2022 - nature.com
Environmental exposures during early life play a critical role in life-course health, yet the
molecular phenotypes underlying environmental effects on health are poorly understood. In …
molecular phenotypes underlying environmental effects on health are poorly understood. In …
Ten years of EWAS
S Wei, J Tao, J Xu, X Chen, Z Wang, N Zhang… - Advanced …, 2021 - Wiley Online Library
Epigenome‐wide association study (EWAS) has been applied to analyze DNA methylation
variation in complex diseases for a decade, and epigenome as a research target has …
variation in complex diseases for a decade, and epigenome as a research target has …
[HTML][HTML] Identical twins carry a persistent epigenetic signature of early genome programming
J van Dongen, SD Gordon, AF McRae… - Nature …, 2021 - nature.com
Monozygotic (MZ) twins and higher-order multiples arise when a zygote splits during pre-
implantation stages of development. The mechanisms underpinning this event have …
implantation stages of development. The mechanisms underpinning this event have …