[HTML][HTML] Gut microbiota in pre-clinical rheumatoid arthritis: From pathogenesis to preventing progression

L Lin, K Zhang, Q Xiong, J Zhang, B Cai, Z Huang… - Journal of …, 2023 - Elsevier
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by progressive
polyarthritis that leads to cartilage and bone damage. Pre-clinical RA is a prolonged state …

Proteoglycans in articular cartilage and their contribution to chondral injury and repair mechanisms

L Alcaide-Ruggiero, R Cugat… - International journal of …, 2023 - mdpi.com
Proteoglycans are vital components of the extracellular matrix in articular cartilage, providing
biomechanical properties crucial for its proper functioning. They are key players in chondral …

Biomechanics of chondrocytes and chondrons in healthy conditions and osteoarthritis: a review of the mechanical characterisations at the microscale

S Pettenuzzo, A Arduino, E Belluzzi, A Pozzuoli… - Biomedicines, 2023 - mdpi.com
Biomechanical studies are expanding across a variety of fields, from biomedicine to
biomedical engineering. From the molecular to the system level, mechanical stimuli are …

Cartilage-related collagens in osteoarthritis and rheumatoid arthritis: from pathogenesis to therapeutics

Z Ouyang, L Dong, F Yao, K Wang, Y Chen… - International Journal of …, 2023 - mdpi.com
Collagens serve essential mechanical functions throughout the body, particularly in the
connective tissues. In articular cartilage, collagens provide most of the biomechanical …

Green biomanufacturing in recombinant collagen biosynthesis: trends and selection in various expression systems

Z Zhao, J Deng, D Fan - Biomaterials Science, 2023 - pubs.rsc.org
Collagen, classically derived from animal tissue, is an all-important protein material widely
used in biomedical materials, cosmetics, fodder, food, etc. The production of recombinant …

Deciphering the fibrotic process: mechanism of chronic radiation skin injury fibrosis

Y Wang, S Chen, S Bao, L Yao, Z Wen, L Xu… - Frontiers in …, 2024 - frontiersin.org
This review explores the mechanisms of chronic radiation-induced skin injury fibrosis,
focusing on the transition from acute radiation damage to a chronic fibrotic state. It reviewed …

Fish scale containing alginate dialdehyde-gelatin bioink for bone tissue engineering

AK Özenler, T Distler, F Tihminlioglu… - Biofabrication, 2023 - iopscience.iop.org
The development of biomaterial inks suitable for biofabrication and mimicking the
physicochemical properties of the extracellular matrix is essential for the application of …

Highly biocompatible smart injectable hydrogel for the management of rheumatoid arthritis

A Kumar, A Ali, Kanika, A Vyawahare… - ACS Biomaterials …, 2023 - ACS Publications
Rheumatoid arthritis (RA) is a chronic inflammatory disease that severely affects joints and
restricts locomotion. Various treatment regimens are available for RA, providing short-term …

Evaluating the Effect of Hypoxia on Human Adult Mesenchymal Stromal Cell Chondrogenesis In Vitro: A Systematic Review

CKI Ranmuthu, CDS Ranmuthu… - International Journal of …, 2022 - mdpi.com
Human adult mesenchymal stromal cells (MSCs) from a variety of sources may be used to
repair defects in articular cartilage by inducing them into chondrogenic differentiation. The …

Biosynthesis of a Functional Fragment of Human Collagen II in Pichia pastoris

K Wang, S Yu, R Sun, K Xu, X Zhao, J Zhou… - ACS Synthetic …, 2024 - ACS Publications
Collagen II (COL2) is the major component of cartilage tissue and is widely applied in
pharmaceuticals, food, and cosmetics. In this study, COL fragments were extracted from …