Intergenerational transmission of trauma effects: putative role of epigenetic mechanisms

R Yehuda, A Lehrner - World psychiatry, 2018 - Wiley Online Library
This paper reviews the research evidence concerning the intergenerational transmission of
trauma effects and the possible role of epigenetic mechanisms in this transmission. Two …

[HTML][HTML] Metabolism disrupting chemicals and metabolic disorders

JJ Heindel, B Blumberg, M Cave, R Machtinger… - Reproductive …, 2017 - Elsevier
The recent epidemics of metabolic diseases, obesity, type 2 diabetes (T2D), liver lipid
disorders and metabolic syndrome have largely been attributed to genetic background and …

ROS, cell senescence, and novel molecular mechanisms in aging and age‐related diseases

P Davalli, T Mitic, A Caporali… - … medicine and cellular …, 2016 - Wiley Online Library
The aging process worsens the human body functions at multiple levels, thus causing its
gradual decrease to resist stress, damage, and disease. Besides changes in gene …

Physical exercise as an epigenetic modulator of brain plasticity and cognition

J Fernandes, RM Arida, F Gomez-Pinilla - Neuroscience & Biobehavioral …, 2017 - Elsevier
A large amount of evidence has demonstrated the power of exercise to support cognitive
function, the effects of which can last for considerable time. An emerging line of scientific …

Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity

M Pigeyre, FT Yazdi, Y Kaur, D Meyre - Clinical science, 2016 - portlandpress.com
In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …

Epigenetic inheritance: concepts, mechanisms and perspectives

I Lacal, R Ventura - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …

Epigenetic inheritance and the missing heritability

M Trerotola, V Relli, P Simeone, S Alberti - Human genomics, 2015 - Springer
Genome-wide association studies of complex physiological traits and diseases consistently
found that associated genetic factors, such as allelic polymorphisms or DNA mutations, only …

Recent progress in epigenetics of obesity

FY Wu, RX Yin - Diabetology & Metabolic Syndrome, 2022 - Springer
Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

[HTML][HTML] Understanding'non-genetic'inheritance: insights from molecular-evolutionary crosstalk

I Adrian-Kalchhauser, SE Sultan, LNS Shama… - Trends in ecology & …, 2020 - cell.com
Understanding the evolutionary and ecological roles of'non-genetic'inheritance (NGI) is
daunting due to the complexity and diversity of epigenetic mechanisms. We draw on insights …

Lamarck rises from his grave: parental environment‐induced epigenetic inheritance in model organisms and humans

Y Wang, H Liu, Z Sun - Biological Reviews, 2017 - Wiley Online Library
Organisms can change their physiological/behavioural traits to adapt and survive in
changed environments. However, whether these acquired traits can be inherited across …