Role of mammalian DNA methyltransferases in development
DNA methylation at the 5-position of cytosine (5mC) plays vital roles in mammalian
development. DNA methylation is catalyzed by DNA methyltransferases (DNMTs), and the …
development. DNA methylation is catalyzed by DNA methyltransferases (DNMTs), and the …
Toxicity of graphene-family nanoparticles: a general review of the origins and mechanisms
L Ou, B Song, H Liang, J Liu, X Feng, B Deng… - Particle and fibre …, 2016 - Springer
Due to their unique physicochemical properties, graphene-family nanomaterials (GFNs) are
widely used in many fields, especially in biomedical applications. Currently, many studies …
widely used in many fields, especially in biomedical applications. Currently, many studies …
Single-cell triple omics sequencing reveals genetic, epigenetic, and transcriptomic heterogeneity in hepatocellular carcinomas
Single-cell genome, DNA methylome, and transcriptome sequencing methods have been
separately developed. However, to accurately analyze the mechanism by which …
separately developed. However, to accurately analyze the mechanism by which …
Mapping DNA methylation with high-throughput nanopore sequencing
DNA chemical modifications regulate genomic function. We present a framework for
mapping cytosine and adenosine methylation with the Oxford Nanopore Technologies …
mapping cytosine and adenosine methylation with the Oxford Nanopore Technologies …
Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity
We report a single-cell bisulfite sequencing (scBS-seq) method that can be used to
accurately measure DNA methylation at up to 48.4% of CpG sites. Embryonic stem cells …
accurately measure DNA methylation at up to 48.4% of CpG sites. Embryonic stem cells …
Insights into epigenetic patterns in mammalian early embryos
R Xu, C Li, X Liu, S Gao - Protein & cell, 2021 - academic.oup.com
Mammalian fertilization begins with the fusion of two specialized gametes, followed by major
epigenetic remodeling leading to the formation of a totipotent embryo. During the …
epigenetic remodeling leading to the formation of a totipotent embryo. During the …
[PDF][PDF] DNA methylation on N6-adenine in C. elegans
In mammalian cells, DNA methylation on the fifth position of cytosine (5mC) plays an
important role as an epigenetic mark. However, DNA methylation was considered to be …
important role as an epigenetic mark. However, DNA methylation was considered to be …
DNA methylation: an epigenetic mark of cellular memory
M Kim, J Costello - Experimental & molecular medicine, 2017 - nature.com
DNA methylation is a stable epigenetic mark that can be inherited through multiple cell
divisions. During development and cell differentiation, DNA methylation is dynamic, but …
divisions. During development and cell differentiation, DNA methylation is dynamic, but …
One-carbon metabolism: linking nutritional biochemistry to epigenetic programming of long-term development
CE Clare, AH Brassington, WY Kwong… - Annual review of …, 2019 - annualreviews.org
One-carbon (1C) metabolism comprises a series of interlinking metabolic pathways that
include the methionine and folate cycles that are central to cellular function, providing 1C …
include the methionine and folate cycles that are central to cellular function, providing 1C …
Rationally engineered nucleic acid architectures for biosensing applications
Development of biosensing platforms plays a key role in research settings for identification
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …
of biomarkers and in clinical applications for diagnostics. Biosensors based on nucleic acids …