Phospholipase A2 enzymes (PLA 2 s) comprise a superfamily that is generally divided into
six subfamilies known as cytosolic PLA 2 s (cPLA 2 s), calcium-independent PLA 2 s (iPLA 2 …

Tumour angiogenesis is the formation of new blood vessels to support the growth of a
tumour. This process is critical for tumour progression and metastasis, making it an attractive …

The bark of Cinnamomum cassia (C. cassia) has been used for the management of coronary
heart disease (CHD) and diabetes mellitus. C. cassia may target the vasculature, as it …

Cell secretion is an important mechanism for stem cell-based therapeutic angiogenesis,
along with cell differentiation to vascular endothelial cells or smooth muscle cells. Cell …

The role of angiogenesis in tumor growth and metastasis is well established. Identification of
a small molecule that blocks tumor angiogenesis and is safe and affordable has been a …

Understanding the molecular basis and target of traditional medicine is critical for drug
development. Celastrol, derived from Trypterygium wilfordii Hook F.(“Thunder of God Vine”) …

Natural biflavonoids, such as amentoflavone, bilobetin, ginkgetin, isoginkgetin,
taiwaniaflavone, morelloflavone, delicaflavone, hinokiflavone, and other derivatives (~ 40 …

Parkinson's disease (PD) is characterized by the progressive degeneration of dopaminergic
neurons in substantia nigra pars compacta (SNpc). Mitochondrial dysfunction and cell …

STAT3 has been strongly implicated in human malignancies, and constitutive activation of
STAT3 serves a crucial role in cell survival, angiogenesis, immune evasion, and …

Background: Biflavonoids belong to a subclass of the plant flavonoids family and are limited
to several species in the plant kingdom. In the literature, biflavonoids are extensively …