Abdominal aortic aneurysm (AAA) is a chronic vascular degenerative disease featured by
progressive dilation and remodeling of the vascular wall, which may lead to aortic rupture …

Objective: We examined the pathogenic significance of VEGF (vascular endothelial growth
factor)-A in experimental abdominal aortic aneurysms (AAAs) and the translational value of …

Aortic aneurysm is a permanent focal dilation of the aorta. It is usually an asymptomatic
disease but can lead to sudden death due to aortic rupture. Aortic aneurysm-related …

Background The analysis of the correlation between blood flow and aortic pathology through
computational fluid dynamics (CFD) shows promise in predicting disease progression, the …

Objective—Recent evidence suggests an important role for angiotensin-converting enzyme
2 (ACE2) in limiting abdominal aortic aneurysm (AAA). This study examined the effect of …

Vascular disease is the leading health problem worldwide. Vascular microenvironment
encompasses diverse cell types, including those within the vascular wall, blood cells …

Objective Mural angiogenesis and macrophage accumulation are two pathologic hallmarks
of abdominal aortic aneurysm (AAA) disease. The heterodimeric transcription factor hypoxia …

Objectives Currently there is no drug therapy for abdominal aortic aneurysm (AAA) and most
previous investigations have focused on imaging rather than clinical outcomes. The aim of …

Aims To evaluate if ticagrelor, an effective platelet inhibitor without known non-responders,
could inhibit growth of small abdominal aortic aneurysms (AAAs). Methods and results In this …

Abdominal aortic aneurysm (AAA) is a potentially fatal vascular disease, but the underlying
mechanisms remain unknown. Here, we tested the hypothesis that erythropoietin (EPO) may …