Systematic review and meta-analysis of interventions to slow progression of abdominal aortic aneurysm in mouse models
Objective: There are no current effective abdominal aortic aneurysm (AAA) drug therapies.
An important limitation of most preclinical studies is that they test the effect of drugs on AAA …
An important limitation of most preclinical studies is that they test the effect of drugs on AAA …
[HTML][HTML] Fucoidan attenuates angiotensin II-induced abdominal aortic aneurysms through the inhibition of c-Jun N-terminal kinase and nuclear factor κB activation
Background Rupture of abdominal aortic aneurysm (AAA) is one of the leading causes of
sudden death among the elderly. Most incidental AAAs are below the threshold for …
sudden death among the elderly. Most incidental AAAs are below the threshold for …
Activated invariant natural killer T cells infiltrate aortic tissue as key participants in abdominal aortic aneurysm pathology
T Miao, T Wang, T Feng, D Yuan, Q Guo, F Xiong… - …, 2021 - Wiley Online Library
Adaptive immunity and innate immunity have been implicated in the pathogenesis of
abdominal aortic aneurysm (AAA), and damage and remodelling in the tunica media are a …
abdominal aortic aneurysm (AAA), and damage and remodelling in the tunica media are a …
Photobiomodulation and estrogen stabilize mitochondrial membrane potential in angiotensin–II challenged porcine aortic smooth muscle cells
Rupture of Abdominal aortic aneurysm (AAA) is among the 15 leading causes of death after
age 65. Using high frequency ultrasound, we showed that photobiomodulation (PBM) …
age 65. Using high frequency ultrasound, we showed that photobiomodulation (PBM) …
Aortic to caudal vena cava ratio measurements using abdominal ultrasound are increased in dogs with confirmed systemic hypertension
M Holland, J Hudson, Y Bao… - Veterinary Radiology & …, 2020 - Wiley Online Library
Chronically sustained systemic hypertension in dogs can damage the kidneys, eye, brain,
heart, and vessels. In human medicine, systemic hypertension has been implicated as the …
heart, and vessels. In human medicine, systemic hypertension has been implicated as the …
MicroRNA‐29a‐3p regulates abdominal aortic aneurysm development and progression via direct interaction with PTEN
Y Zhou, M Wang, J Zhang, P Xu… - Journal of Cellular …, 2020 - Wiley Online Library
Various research studies have been conducted in deducing the role of microRNAs
(miRNAs) in the pathogenesis and physiological processes of various systematic diseases …
(miRNAs) in the pathogenesis and physiological processes of various systematic diseases …
[HTML][HTML] Aortic and systemic arterial stiffness responses to acute exercise in patients with small abdominal aortic aneurysms
Objective/background Elevated arterial stiffness is a characteristic of abdominal aortic
aneurysm (AAA), and is associated with AAA growth and cardiovascular mortality. A bout of …
aneurysm (AAA), and is associated with AAA growth and cardiovascular mortality. A bout of …
Top 10 candidate aortic disease trials
RL Dalman, A Wanhainen, K Mani… - Journal of Internal …, 2020 - Wiley Online Library
Aortic pathologies such as aneurysm, dissection and trauma are relatively common and
potentially fatal diseases. Over the past two decades, we have experienced unprecedented …
potentially fatal diseases. Over the past two decades, we have experienced unprecedented …
Glucagon-Like Peptide-1 Inhibits the Progression of Abdominal Aortic Aneurysm in Mice: The Earlier, the Better
X Zhao, Z Cheng, H Zhang, Y Guo, L Zhao… - … Drugs and Therapy, 2023 - Springer
Abstract Objectives Glucagon-like peptide-1 (GLP-1) has a cardiovascular protective effect
by preventing abdominal aortic aneurysm (AAA) formation. However, it is unclear at what …
by preventing abdominal aortic aneurysm (AAA) formation. However, it is unclear at what …
[HTML][HTML] Abdominal aortic aneurysm: natural history, pathophysiology and translational perspectives
G Accarino, AN Giordano, M Falcone… - Translational …, 2022 - ncbi.nlm.nih.gov
An abdominal aortic aneurysm (AAA) is a degenerative pathology that affects the infrarenal
segment of the aorta, leading to its progressive dilatation and eventually rupture. The …
segment of the aorta, leading to its progressive dilatation and eventually rupture. The …