Objective: Atrial fibrillation (AF) is the most common form of sustained arrhythmia. Several
molecular pathways associated with the pathogenesis of AF also participate in the initiation …

Cysteinyl-leukotrienes (cys-LTs) are 5-lipoxygenase-derived lipid mediators involved in the
pathogenesis and progression of inflammatory disorders, in particular asthma. We have …

Background: Abdominal aortic aneurysm (AAA) is a chronic degenerative inflammatory
disease. Multi-factors including genetic, environmental and lifestyle factors determine the …

Abdominal aortic aneurysm (AAA) is an important vascular disease carrying significant
mortality implications due to the risk of aneurysm rupture. Current management relies …

Sustained systemic hypertension (SH) has been shown to cause target organ damage to
various tissues in dogs and cats, including the aorta. Aortic dilatation occurs most commonly …

Background: Abdominal aortic aneurysm (AAA) refers to localized dilation of abdominal
aorta. AAA is largely asymptomatic, but aneurysmal rupture results in a high mortality rate …

Endoplasmic reticulum (ER) and mitochondria are crucial organelles for cell homeostasis
and alterations of these organelles have been implicated in cardiovascular disease …

Abdominal aortic aneurysm (AAA) is a significant source of mortality worldwide and carries a
mortality of greater than 80% after rupture. Despite extensive efforts to develop …

Pharmacotherapy for abdominal aortic aneurysm (AAA) can be useful for prevention,
especially in people at higher risk, for slowing down AAA progression, as well as for post …

Background The role of atherosclerosis in the pathogenesis of abdominal aortic aneurysm
(AAA) is controversial. Atherosclerosis-associated peripheral artery disease (PAD) has been …