Cryptococcus neoformans is an encapsulated fungal pathogen that causes infection in
immunocompromised individuals such as HIV patients, organ transplant patients …

Respiratory fungal infection is a severe clinical problem, especially in patients with
compromised immune functions. Aspergillus, Cryptococcus, Pneumocystis, and endemic …

Inhaled corticosteroids (ICS) have limited efficacy in reducing chronic obstructive pulmonary
disease (COPD) exacerbations and increase pneumonia risk, through unknown …

Immune responses to lung infections must be tightly regulated in order to permit pathogen
eradication while maintaining organ function. Exuberant or dysregulated inflammation can …

Abstract RIG-I–like receptors (RLR) are cytosolic RNA sensors that signal through the MAVS
adaptor to activate IFN responses against viruses. Whether the RLR family has broader …

Cryptococcus deneoformans is an opportunistic fungal pathogen that infects the lungs via
airborne transmission and frequently causes fatal meningoencephalitis. Claudins (Cldns), a …

Cryptococcus neoformans is an opportunistic human pathogen, which causes serious
disease in immunocompromised hosts. Infection with this pathogen is particularly relevant in …

Influenza A virus (IAV) infects millions of people annually and predisposes to secondary
bacterial infections. Inhalation of fungi within the Cryptococcus complex causes pulmonary …

Cryptococcus spp. are yeast-type opportunistic fungal pathogens with thick polysaccharide
capsules that infect the lungs via airborne routes and frequently cause fatal …

IL-17A is a proinflammatory cytokine produced by many types of innate immune cells and
Th17 cells and is involved in the elimination of extracellularly growing microorganisms, yet …