DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) in mouse promoter regions demonstrating tissue-specific gene expression
S Yagi, K Hirabayashi, S Sato, W Li… - Genome …, 2008 - genome.cshlp.org
DNA methylation constitutes an important epigenetic regulation mechanism in many
eukaryotes, although the extent of DNA methylation in the regulation of gene expression in …
eukaryotes, although the extent of DNA methylation in the regulation of gene expression in …
Benzopyrene exposure disrupts DNA methylation and growth dynamics in breast cancer cells
B Sadikovic, DI Rodenhiser - Toxicology and applied pharmacology, 2006 - Elsevier
Exposures to environmental carcinogens and unhealthy lifestyle choices increase the
incidence of breast cancer. One such compound, benzo (a) pyrene (BaP), leads to covalent …
incidence of breast cancer. One such compound, benzo (a) pyrene (BaP), leads to covalent …
Epigenetic events associated with breast cancer and their prevention by dietary components targeting the epigenome
SI Khan, P Aumsuwan, IA Khan… - Chemical research in …, 2012 - ACS Publications
Aberrant epigenetic alterations in the genome such as DNA methylation and chromatin
remodeling play a significant role in breast cancer development. Since epigenetic …
remodeling play a significant role in breast cancer development. Since epigenetic …
MSRE-PCR for analysis of gene-specific DNA methylation
AA Melnikov, RB Gartenhaus, AS Levenson… - Nucleic acids …, 2005 - academic.oup.com
Abnormal DNA methylation is observed in certain promoters of neoplastic cells, although the
likelihood of methylation for each individual promoter varies. Simultaneous analysis of many …
likelihood of methylation for each individual promoter varies. Simultaneous analysis of many …
Green tea polyphenol epigallocatechin 3-gallate, contributes to the degradation of DNMT3A and HDAC3 in HCT 116 human colon cancer cells
VR Moseley, J Morris, RW Knackstedt… - Anticancer …, 2013 - ar.iiarjournals.org
Background: Colon cancer is still the second leading cause of cancer deaths in the United
States. Epigenetic gene silencing involving DNA methyltransferases (DNMTs) and histone …
States. Epigenetic gene silencing involving DNA methyltransferases (DNMTs) and histone …
HDAC3 overexpression and colon cancer cell proliferation and differentiation
CC Spurling, CA Godman, EJ Noonan… - … in cooperation with …, 2008 - Wiley Online Library
An immunohistochemical analysis of human colorectal adenocarcinomas showed that
cancer cells express widely varying levels of HDAC3. The SW480 colon cancer cell line was …
cancer cells express widely varying levels of HDAC3. The SW480 colon cancer cell line was …
[HTML][HTML] Prediction of methylated CpGs in DNA sequences using a support vector machine
DNA methylation plays a key role in the regulation of gene expression. The most common
type of DNA modification consists of the methylation of cytosine in the CpG dinucleotide. At …
type of DNA modification consists of the methylation of cytosine in the CpG dinucleotide. At …
DNA methylation in cancer development, diagnosis and therapy—multiple opportunities for genotoxic agents to act as methylome disruptors or remediators
J Lewandowska, A Bartoszek - Mutagenesis, 2011 - academic.oup.com
The role of DNA methylation and recently discovered hydroxymethylation in the function of
the human epigenome is currently one of the hottest topics in the life sciences. Progress in …
the human epigenome is currently one of the hottest topics in the life sciences. Progress in …
Oncogenic and invasive potentials of human macrophage-stimulating protein receptor, the RON receptor tyrosine kinase
MH Wang, D Wang, YQ Chen - Carcinogenesis, 2003 - academic.oup.com
The product of the RON (recepteur d'origine nantais) gene belongs to the MET proto-
oncogene family, a distinct subfamily of receptor tyrosine kinases. The ligand of RON was …
oncogene family, a distinct subfamily of receptor tyrosine kinases. The ligand of RON was …
Epigenetic mechanisms of tamoxifen resistance in luminal breast cancer
HA Abdel-Hafiz - Diseases, 2017 - mdpi.com
Breast cancer is one of the most common cancers and the second leading cause of cancer
death in the United States. Estrogen receptor (ER)-positive cancer is the most frequent …
death in the United States. Estrogen receptor (ER)-positive cancer is the most frequent …