Sex differential in methylation patterns of selected genes in Singapore Chinese
B Sarter, TI Long, WH Tsong, WP Koh, MC Yu… - Human genetics, 2005 - Springer
To date there have been few reports of a gender difference in methylation levels of genes.
When examining the methylation levels of four autosomal genes (ESR1, MTHFR, CALCA …
When examining the methylation levels of four autosomal genes (ESR1, MTHFR, CALCA …
Detection of hypermethylated genes in tumor and plasma of cervical cancer patients
HJ Yang, VWS Liu, Y Wang, KYK Chan, PCK Tsang… - Gynecologic …, 2004 - Elsevier
Objective. The aim of this study is to investigate the prevalence of promotor CpG island
methylation of the death-associated protein kinase (DAPK), p16, and O6-methylguanine …
methylation of the death-associated protein kinase (DAPK), p16, and O6-methylguanine …
Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation
D Capper, T Gaiser, C Hartmann, A Habel… - Acta …, 2009 - Springer
Tumour necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL/Apo2L) is a
promising cancer drug. However, many tumours are resistant to TRAIL-based therapies …
promising cancer drug. However, many tumours are resistant to TRAIL-based therapies …
Lysophosphatidic acid receptors in cancer pathobiology.
T Tsujiuchi, M Araki, M Hirane, Y Dong… - Histology and …, 2013 - europepmc.org
Lysophosphatidic acid (LPA) receptors (LPA₁ to LPA₆) are G protein-coupled
transmembrane and mediate a variety of biological responses through the binding of LPA …
transmembrane and mediate a variety of biological responses through the binding of LPA …
DNMT1 is a component of a multiprotein DNA replication complex
PM Vertino, JA Sekowski, JM Coll, N Applegreen… - Cell cycle, 2002 - Taylor & Francis
DNA methylation is a major determinant of epigenetic inheritance and plays an important
role in genome stability. The accurate propagation of DNA methylation patterns with cell …
role in genome stability. The accurate propagation of DNA methylation patterns with cell …
Differential expression of the epigenetic methylation-related protein DNMT1 by breast cancer molecular subtype and stromal histology
E Shin, YK Lee, JS Koo - Journal of translational medicine, 2016 - Springer
Background We assessed the expression of methylation-related proteins 5-meC, DNMT1,
and ISL-1 in breast cancer and evaluated their relationship to clinicopathological factors …
and ISL-1 in breast cancer and evaluated their relationship to clinicopathological factors …
Transmembrane protein 88 (TMEM88) promoter hypomethylation is associated with platinum resistance in ovarian cancer
M de Leon, H Cardenas, E Vieth, R Emerson… - Gynecologic …, 2016 - Elsevier
Objectives Epigenetic alterations have been implicated in the development of platinum
resistance in ovarian cancer (OC). In this study, we aimed to identify DNA methylation …
resistance in ovarian cancer (OC). In this study, we aimed to identify DNA methylation …
PLA2R1: expression and function in cancer
D Bernard, D Vindrieux - Biochimica et Biophysica Acta (BBA)-Reviews on …, 2014 - Elsevier
The phospholipase A2 receptor 1 (PLA2R1 or PLA2R) was isolated twenty years ago for its
ability to bind several secretory phospholipase A2 proteins (sPLA2). Since its identification, it …
ability to bind several secretory phospholipase A2 proteins (sPLA2). Since its identification, it …
Epigenetic silencing of ALDH1L1, a metabolic regulator of cellular proliferation, in cancers
NV Oleinik, NI Krupenko, SA Krupenko - Genes & Cancer, 2011 - journals.sagepub.com
FDH (10-formyltetrahydrofolate dehydrogenase, the product of the ALDH1L1 gene), a major
folate-metabolizing enzyme in the cytosol, is involved in the regulation of cellular …
folate-metabolizing enzyme in the cytosol, is involved in the regulation of cellular …