Malignant transformation is now known to require a series of molecular alterations that
disrupt a limited number of pathways including autocrine and paracrine responses to growth …

The H19 imprinted gene locus is regulated by an upstream 2 kb imprinting control region
(ICR) that influences allele-specific expression, DNA methylation [1], and replication timing …

Regeneration of auditory hair cells in adult mammals is challenging. It is also difficult to track
the sources of regenerated hair cells, especially in vivo. Previous paper found newly …

Among other targets, DNA demethylating agents are known to affect the sister chromatid
exchange (SCE) frequency in mammalian cells in vitro. The SCE increase appears to be …

The pattern of DNA methylation established during embryonic development is necessary for
the control of gene expression and is preserved during the replicative process. DNA regions …

DNA methylation level and pattern of human metaphase chromosomes from extraembryonic
tissues (chorionic villi and placental fibroblasts) were analysed in situ. The DNA methylation …

The aim of this paper is to verify whether the control played by poly (ADP‐ribosyl)‐ation on
genomic DNA methylation, and in particular on CpG islands, can also be seen on foreign …

DNA methylation is an epigenetical mechanism that plays crucial roles in cellular
differentiation and tissue development in embryogenesis. The aim of the present study was …

Global hypomethylation of genes and repetitive sequences, as well as hypermethylation of
certain genes known to be involved in tumor suppression, are observed concurrently in …

The methylation pattern at CpG sites of a housekeeping gene correlates with the likelihood
of mutation. Mucopolysaccharidosis (MPS) type II, an X‐linked disorder, results from the …