Purpos e Folic acid (FA) is an emerging nutritional factor in the pathogenesis of diverse
neurodegenerative disorders by still unknown mechanisms. The hippocampus is altered …

Class I HLA genes are expressed in almost all tissues, but expression is low or undetectable
in many neuroblastomas. We analysed class I HLA methylation in normal tissues and in 28 …

Dysregulation of CpG-methylation is a common feature of many human cancers and tumour
suppressor genes can be silenced by hypermethylation. Recently, 2 methyl-CpG-binding …

Recently, an influential sequencing study found that more than 1700 genes had non-silent
mutations in either a breast or colorectal cancer, out of just 11 breast and 11 colorectal tumor …

We have developed a new approach to the analysis of hypomethylated CpG patterns within
predetermined, megabase long, genome regions. The approach, which we term Non …

About half of all genes have a CpG island surrounding the promoter and transcription start
site. Most promoter CpG islands are normally unmethylated in all tissues, irrespective of the …

Age‐related increases in the expression of glial fibrillary acidic protein (GFAP) in many brain
regions are observed in short‐and long‐lived mammals. Possible genomic mechanisms for …

В обзоре обсуждается, каким образом такие эпигенетические модификации, как
моноаллельное меr тилирование ДНК, ковалентные модификации гистонов …

Myf‐3 is the human homologue of the murine Myo‐D1 gene involved in muscle‐cell
differentiation. Using Southern blot analysis, we examined methylation of Myf‐3 in …

This study examined hypermethylated and downregulated genes specific to carbon
tetrachloride (CCl4) by Methyl-Seq analysis combined with expression microarray analysis …