A dominant role for the methyl-CpG-binding protein Mbd2 in controlling Th2 induction by dendritic cells
Dendritic cells (DCs) direct CD4+ T-cell differentiation into diverse helper (Th) subsets that
are required for protection against varied infections. However, the mechanisms used by DCs …
are required for protection against varied infections. However, the mechanisms used by DCs …
DNA methylation signatures of peripheral leukocytes in schizophrenia
M Kinoshita, S Numata, A Tajima, S Shimodera… - Neuromolecular …, 2013 - Springer
Schizophrenia (SCZ) is a complex psychiatric disease with a lifetime morbidity rate of 0.5–
1.0%. To date, aberrant DNA methylation in SCZ has been reported in several studies …
1.0%. To date, aberrant DNA methylation in SCZ has been reported in several studies …
Potential metabolic biomarkers in adult asthmatics
Asthma is the most common chronic airway inflammation, with multiple phenotypes caused
by complicated interactions of genetic, epigenetic, and environmental factors. To date …
by complicated interactions of genetic, epigenetic, and environmental factors. To date …
Gene and transposable element methylation in great tit (Parus major) brain and blood
Background Studies on vertebrate DNA methylomes have revealed a regulatory role of
tissue specific DNA methylation in relation to gene expression. However, it is not well known …
tissue specific DNA methylation in relation to gene expression. However, it is not well known …
Bisulfite-independent analysis of CpG island methylation enables genome-scale stratification of single cells
Conventional DNA bisulfite sequencing has been extended to single cell level, but the
coverage consistency is insufficient for parallel comparison. Here we report a novel method …
coverage consistency is insufficient for parallel comparison. Here we report a novel method …
Hypomethylation within gene promoter regions and type 1 diabetes in discordant monozygotic twins
E Elboudwarej, M Cole, FBS Briggs, A Fouts… - Journal of …, 2016 - Elsevier
Genetic susceptibility to type 1 diabetes (T1D) is well supported by epidemiologic evidence;
however, disease risk cannot be entirely explained by established genetic variants identified …
however, disease risk cannot be entirely explained by established genetic variants identified …
Active DNA demethylation in post-mitotic neurons: a reason for optimism
Over the last several years proteins involved in base excision repair (BER) have been
implicated in active DNA demethylation. We review the literature supporting BER as a …
implicated in active DNA demethylation. We review the literature supporting BER as a …
ICF-specific DNMT3B dysfunction interferes with intragenic regulation of mRNA transcription and alternative splicing
Hypomorphic mutations in DNA-methyltransferase DNMT3B cause majority of the rare
disorder Immunodeficiency, Centromere instability and Facial anomalies syndrome cases …
disorder Immunodeficiency, Centromere instability and Facial anomalies syndrome cases …
Advances in epigenetic mechanisms of chick embryo heat acclimation
P Xu, H Lin, H Jiao, J Zhao, X Wang - World's Poultry Science …, 2022 - Taylor & Francis
The environment is closely related to the healthy rearing of animals. As an environmental
stressor, heat stress has been paid close attention by practitioners. The high-temperature …
stressor, heat stress has been paid close attention by practitioners. The high-temperature …
Integrative analysis of methylome and transcriptome in human blood identifies extensive sex-and immune cell-specific differentially methylated regions
S Mamrut, N Avidan, E Staun-Ram, E Ginzburg… - Epigenetics, 2015 - Taylor & Francis
The relationship between DNA methylation and gene expression is complex and elusive. To
further elucidate these relations, we performed an integrative analysis of the methylome and …
further elucidate these relations, we performed an integrative analysis of the methylome and …