Molecular mechanisms underlying protective role of quercetin in attenuating Alzheimer's disease

E Zaplatic, M Bule, SZA Shah, MS Uddin, K Niaz - Life sciences, 2019 - Elsevier
Quercetin belongs to the flavonoids family, which is present in most of the plants including
fruits, vegetables, green tea and even in red wine having antioxidant activities. It is available …

The role matrix metalloproteinases in the production of aortic aneurysm

SW Rabkin - Progress in molecular biology and translational …, 2017 - Elsevier
Matrix metalloproteinases (MMPs) have been implicated in the pathogenesis of aortic
aneurysm because the histology of thoracic aortic aneurysm (TAA) and abdominal aortic …

Obesity-related oxidative stress: the impact of physical activity and diet manipulation

CJ Huang, MJ McAllister, AL Slusher, HE Webb… - Sports medicine …, 2015 - Springer
Obesity-related oxidative stress, the imbalance between pro-oxidants and antioxidants (eg,
nitric oxide), has been linked to metabolic and cardiovascular disease, including endothelial …

Oxidative stress and abdominal aortic aneurysm: potential treatment targets

TI Emeto, JV Moxon, M Au, J Golledge - Clinical science, 2016 - portlandpress.com
Abdominal aortic aneurysm (AAA) is a significant cause of mortality in older adults. A key
mechanism implicated in AAA pathogenesis is inflammation and the associated production …

MMPs and ADAMs/ADAMTS inhibition therapy of abdominal aortic aneurysm

Y Li, W Wang, L Li, RA Khalil - Life sciences, 2020 - Elsevier
Abdominal aortic aneurysm (AAA) is a chronic vascular degenerative disease featured by
progressive dilation and remodeling of the vascular wall, which may lead to aortic rupture …

Cellular signaling in abdominal aortic aneurysm

Z Li, W Kong - Cellular signalling, 2020 - Elsevier
Abdominal aortic aneurysms (AAAs) are highly lethal cardiovascular diseases without
effective medications. However, the molecular and signaling mechanisms remain unclear. A …

[HTML][HTML] Histological changes, lipid metabolism, and oxidative and endoplasmic reticulum stress in the liver of laying hens exposed to cadmium concentrations

MK Zhu, HY Li, LH Bai, LS Wang, XT Zou - Poultry science, 2020 - Elsevier
The objective of this study was to determine the effects of cadmium (Cd) on histological
changes, lipid metabolism, and oxidative and endoplasmic reticulum (ER) stress in the liver …

Qingfei Jiedu decoction inhibits PD-L1 expression in lung adenocarcinoma based on network pharmacology analysis, molecular docking and experimental …

J Pan, H Yang, L Zhu, Y Lou, B Jin - Frontiers in Pharmacology, 2022 - frontiersin.org
Objective: We aim at investigating the molecular mechanisms through which the Qingfei
Jiedu decoction (QFJDD) regulates PD-L1 expression in lung adenocarcinoma (LUAD) …

The role of endothelial dysfunction in aortic aneurysms

G Siasos, K Mourouzis, E Oikonomou… - Current …, 2015 - ingentaconnect.com
Abdominal aortic aneurysm is a vascular disease which, despite the fact that it shares
common risk factors with atherosclerosis, develops in parallel but as a partly independent …

Quercetin Downregulates Cyclooxygenase‐2 Expression and HIF‐1α/VEGF Signaling‐Related Angiogenesis in a Mouse Model of Abdominal Aortic Aneurysm

L Wang, H Wu, L Xiong, X Liu, N Yang… - BioMed Research …, 2020 - Wiley Online Library
Objective. Abdominal aortic aneurysm (AAA) development has been characterized by
increased expression of vascular endothelial growth factor (VEGF), which contributes to …