Guide for current nutrigenetic, nutrigenomic, and nutriepigenetic approaches for precision nutrition involving the prevention and management of chronic diseases …
O Ramos-Lopez, FI Milagro, H Allayee… - Lifestyle …, 2017 - karger.com
Chronic diseases, including obesity, are major causes of morbidity and mortality in most
countries. The adverse impacts of obesity and associated comorbidities on health remain a …
countries. The adverse impacts of obesity and associated comorbidities on health remain a …
[HTML][HTML] Polymorphisms, diet and nutrigenomics
Every human being possesses an exclusive nutritional blueprint inside their genes.
Bioactive food components and nutrients affect the expression of such genes. Nutrigenomics …
Bioactive food components and nutrients affect the expression of such genes. Nutrigenomics …
The co‐regulatory networks of tumor suppressor genes, oncogenes, and miRNAs in colorectal cancer
ML Slattery, JS Herrick, LE Mullany… - Genes …, 2017 - Wiley Online Library
Tumor suppressor genes (TSGs) and oncogenes (OG) are involved in carcinogenesis.
MiRNAs also contribute to cellular pathways leading to cancer. We use data from 217 …
MiRNAs also contribute to cellular pathways leading to cancer. We use data from 217 …
The NF-κB signalling pathway in colorectal cancer: associations between dysregulated gene and miRNA expression
ML Slattery, LE Mullany, L Sakoda… - Journal of cancer …, 2018 - Springer
Background The nuclear factor-kappa B (NF-κB) signalling pathway is a regulator of immune
response and inflammation that has been implicated in the carcinogenic process. We …
response and inflammation that has been implicated in the carcinogenic process. We …
Dysregulated genes and miRNAs in the apoptosis pathway in colorectal cancer patients
ML Slattery, LE Mullany, LC Sakoda, RK Wolff… - Apoptosis, 2018 - Springer
Apoptosis is genetically regulated and involves intrinsic and extrinsic pathways. We
examined 133 genes within these pathways to identify whether they are expressed …
examined 133 genes within these pathways to identify whether they are expressed …
[HTML][HTML] The p53-signaling pathway and colorectal cancer: Interactions between downstream p53 target genes and miRNAs
ML Slattery, LE Mullany, RK Wolff, LC Sakoda… - Genomics, 2019 - Elsevier
Introduction We examined expression of genes in the p53-signaling pathway. We determine
if genes that have significantly different expression in carcinoma tissue compared to normal …
if genes that have significantly different expression in carcinoma tissue compared to normal …
The MAPK-signaling pathway in colorectal cancer: dysregulated genes and their association with micrornas
ML Slattery, LE Mullany, LC Sakoda… - Cancer …, 2018 - journals.sagepub.com
Mitogen-activated protein kinase (MAPK) pathways regulate many cellular functions
including cell proliferation and apoptosis. We examined associations of differential gene and …
including cell proliferation and apoptosis. We examined associations of differential gene and …
Genome-wide characterization of genetic variants and putative regions under selection in meat and egg-type chicken lines
Background Meat and egg-type chickens have been selected for several generations for
different traits. Artificial and natural selection for different phenotypes can change frequency …
different traits. Artificial and natural selection for different phenotypes can change frequency …
Precision nutrition to target lipid metabolism alterations in cancer
MG de Cedrón, AR de Molina - Precision medicine for investigators …, 2020 - Elsevier
Cancer relies on genetic and environmental factors, along with the interaction between each
other. Together with the host genome, environmental factors associated with lifestyle …
other. Together with the host genome, environmental factors associated with lifestyle …
[HTML][HTML] Novel insights into the molecular mechanisms underlying risk of colorectal cancer from smoking and red/processed meat carcinogens by modeling exposure …
Tobacco smoke and red/processed meats are well-known risk factors for colorectal cancer
(CRC). Most research has focused on studies of normal colon biopsies in epidemiologic …
(CRC). Most research has focused on studies of normal colon biopsies in epidemiologic …