Abdominal aortic aneurysm (AAA) is a severe vascular disease and a major public health
issue with an unmet medical need for therapy. This disease is featured by a progressive …

Vascular repair upon vessel injury is essential for the maintenance of arterial homeostasis
and function. Stem/progenitor cells were demonstrated to play a crucial role in regeneration …

BACKGROUND: Medial arterial calcification is a chronic systemic vascular disorder distinct
from atherosclerosis and is commonly observed in patients with chronic kidney disease …

Cardiovascular calcification is a significant public health issue whose pathophysiology is not
fully understood. NOR-1 regulates critical processes in cardiovascular remodeling, but its …

Background N6-methyladenosine (m6A) is found in almost all nuclear RNAs of eukaryotes,
playing an important and diverse role in many biological processes. Nonetheless, the roles …

Endothelial dysfunction (ED) is critical in the development and progression of cardiovascular
(CV) disorders, yet effective therapeutic targets for ED remain elusive due to limited …

MAIT cells are multifunctional innate-like effector cells recognizing bacterial-derived vitamin
B metabolites presented by the non-polymorphic MHC class I related protein 1 (MR1) …

Background Atrial cardiomyopathy (ACM) is responsible for atrial fibrillation (AF) and
thromboembolic events. Diabetes mellitus (DM) is an important risk factor for ACM. However …

Background Acute myocardial infarction (AMI) is one of the leading causes of death
worldwide. The etiology of AMI is complex and has not been fully defined. In recent years …

Neuron-derived orphan receptor 1 (NOR1), also called nuclear receptor subfamily 4 group A
member 3 (NR4A3), is a nuclear receptor belonging to the NR4A family. Since no …