Depending on the stage of their intervention with the viral replicative cycle, human
immunodeficiency virus inhibitors could be divided into the following groups:(i) adsorption …

Being an important constituent of naturally occurring lactones with diverse biological
activities and as a pivotal intermediate in heterocycle synthesis, the isocoumarin motif has …

High-affinity ligands of the reverse transcriptase of human immunodeficiency virus type 1
(HIV-1) were isolated by the SELEX procedure (systematic evolution of ligands by …

Derivatives of pyridinones were found to inhibit human immunodeficiency virus type 1 (HIV-
1) reverse transcriptase (RT) activity and prevent the spread of HIV-1 infection in cell culture …

The telomerase inhibitor griseorhodin A is probably the most heavily oxidized bacterial
polyketide known and features a unique epoxyspiroketal moiety crucial for its activity. To …

Human immunodeficiency virus type 1 (HIV-1)-specific pyridinone reverse transcriptase (RT)
inhibitors prevent HIV-1 replication in cell culture (ME Goldman, JH Nunberg, JA O'Brien, JC …

Covering: 1999–2003Marine invertebrates and a growing number of marine bacteria are the
sources of novel, bioactive secondary metabolites. Structurally, many of these compounds …

Isolation, biological activity and synthesis of benzannulated spiroketal natural products -
Natural Product Reports (RSC Publishing) DOI:10.1039/B911514P Royal Society of Chemistry …

We found that a group of rubromycins and their analogues, a class of quinone antibiotics
that possesses benzofuran and benzodipyran rings to form a spiroketal system, strongly …

Inhibitors of HIV reverse transcriptase (RT) are important drugs for the treatment of acquired
immuno-deficiency syndrome (AIDS). One approach to identify novel inhibitors of HIV-1-RT …