[HTML][HTML] How vascular smooth muscle cell phenotype switching contributes to vascular disease
G Cao, X Xuan, J Hu, R Zhang, H Jin… - Cell Communication and …, 2022 - Springer
Vascular smooth muscle cells (VSMCs) are the most abundant cell in vessels. Earlier
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
experiments have found that VSMCs possess high plasticity. Vascular injury stimulates …
Type III collagen (COL3A1): Gene and protein structure, tissue distribution, and associated diseases
H Kuivaniemi, G Tromp - Gene, 2019 - Elsevier
Abstract Collagen alpha-1 (III) chain, also known as the alpha 1 chain of type III collagen, is
a protein that in humans is encoded by the COL3A1 gene. Three alpha 1 chains are …
a protein that in humans is encoded by the COL3A1 gene. Three alpha 1 chains are …
Role of vascular smooth muscle cell phenotypic switching and calcification in aortic aneurysm formation: involvement of vitamin K-dependent processes
P Petsophonsakul, M Furmanik, R Forsythe… - … , and vascular biology, 2019 - Am Heart Assoc
Aortic aneurysm is a vascular disease whereby the ECM (extracellular matrix) of a blood
vessel degenerates, leading to dilation and eventually vessel wall rupture. Recently, it was …
vessel degenerates, leading to dilation and eventually vessel wall rupture. Recently, it was …
Gut microbiota–derived trimethylamine N-oxide contributes to abdominal aortic aneurysm through inflammatory and apoptotic mechanisms
Background: Large-scale human and mechanistic mouse studies indicate a strong
relationship between the microbiome-dependent metabolite trimethylamine N-oxide (TMAO) …
relationship between the microbiome-dependent metabolite trimethylamine N-oxide (TMAO) …
Abdominal aortic aneurysms
N Sakalihasan, JB Michel, A Katsargyris… - Nature reviews Disease …, 2018 - nature.com
An abdominal aortic aneurysm (AAA) is a localized dilatation of the infrarenal aorta. AAA is a
multifactorial disease, and genetic and environmental factors play a part; smoking, male sex …
multifactorial disease, and genetic and environmental factors play a part; smoking, male sex …
Neutrophil extracellular trap degradation by differently polarized macrophage subsets
P Haider, JB Kral-Pointner, J Mayer… - … , and vascular biology, 2020 - Am Heart Assoc
Objective: Macrophages are immune cells, capable to remodel the extracellular matrix,
which can harbor extracellular DNA incorporated into neutrophil extracellular traps (NETs) …
which can harbor extracellular DNA incorporated into neutrophil extracellular traps (NETs) …
[HTML][HTML] Abdominal aortic aneurysm formation with a focus on vascular smooth muscle cells
Abdominal aortic aneurysm (AAA) is a lethal degenerative vascular disease that affects,
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …
mostly, the elder population, with a high mortality rate (> 80%) upon rupture. It features a …
[HTML][HTML] Endothelial dysfunction in the pathogenesis of abdominal aortic aneurysm
Abdominal aortic aneurysm (AAA), defined as a focal dilation of the abdominal aorta beyond
50% of its normal diameter, is a common and potentially life-threatening vascular disease …
50% of its normal diameter, is a common and potentially life-threatening vascular disease …
Incidence and prevalence of thoracic aortic aneurysms: a systematic review and meta-analysis of population-based studies
Thoracic aortic aneurysms (TAA) may grow asymptomatically until they rupture, with a
mortality over 90%. The true incidence and prevalence of this condition is uncertain and …
mortality over 90%. The true incidence and prevalence of this condition is uncertain and …
[HTML][HTML] Aneurysm sac failure to regress after endovascular aneurysm repair is associated with lower long-term survival
TFX O'Donnell, SE Deery, LT Boitano… - Journal of Vascular …, 2019 - Elsevier
Background The early survival advantage of endovascular aneurysm repair (EVAR)
compared with open repair reverses over time, possibly because of higher rates of …
compared with open repair reverses over time, possibly because of higher rates of …