Immunoglobulin A vasculitis (IgAV), formerly known as Henoch-Schönlein purpura, is the
most common systemic vasculitis in children, characterized by diverse clinical …

Complement C4, a key molecule in the complement system that is one of chief constituents
of innate immunity for immediate recognition and elimination of invading microbes, plays an …

OBJECTIVE: To examine epidemiological, clinical, and outcome in Italian children affected
with Henoch Schönlein purpura (HSP). METHODS: Retrospective study of children …

Antibody deficiencies constitute the largest group of symptomatic primary immunodeficiency
diseases. In several patients, mutations in CD19 have been found to underlie disease …

What is the difference between IgA nephropathy and Henoch-Schönlein purpura nephritis?
Henoch-Schönlein purpura nephritis (HSPN) and IgA nephropathy (IgAN) are considered to …

The severity of renal involvement is the major factor determining the long-term outcome of
children with Henoch-Schönlein purpura (HSP) nephritis (HSPN). Approximately 40 …

Henoch-Schönlein purpura (HSP) is a form of systemic vasculitis characterised by vascular
wall deposits of predominally IgA typically involving small vessels in skin, gut and glomeruli …

The complement components C4A, C4B, and factor B, and the HLA-A, B, C, DR, DQ, and
DRw antigens were analyzed in 103 patients (66 Caucasian, 37 black) with systemic lupus …

IgA nephropathy is the most-common primary glomerulonephritis worldwide, and about 20%–
50% of patients develop progressive renal failure. The pathogenesis is still unknown and …

Certain immune complex (IC)-mediated diseases frequently cause hypocomplementemia as
assessed by measurement of serum or plasma C3, C4 or CH50 (third component of the …