The contribution of matrix metalloproteinases and their inhibitors to the development, progression, and rupture of abdominal aortic aneurysms

G Atkinson, R Bianco, K Di Gregoli… - Frontiers in …, 2023 - frontiersin.org
Abdominal aortic aneurysms (AAAs) account for up to 8% of deaths in men aged 65 years
and over and 2.2% of women. Patients with AAAs often have atherosclerosis, and intimal …

Smooth muscle heterogeneity and plasticity in health and aortic aneurysmal disease

Y Hu, Z Cai, B He - International Journal of Molecular Sciences, 2023 - mdpi.com
Vascular smooth muscle cells (VSMCs) are the predominant cell type in the medial layer of
the aorta, which plays a critical role in the maintenance of aortic wall integrity. VSMCs have …

Akkermansia muciniphila Alters Gut Microbiota and Immune System to Improve Cardiovascular Diseases in Murine Model

X He, Y Bai, H Zhou, K Wu - Frontiers in microbiology, 2022 - frontiersin.org
The gut microbiota plays an important role in a variety of cardiovascular diseases. The
probiotics screened based on microbiota can effectively improve metabolism and immune …

[HTML][HTML] Inhibition of peptidyl arginine deiminase 4-dependent neutrophil extracellular trap formation reduces angiotensin II-induced abdominal aortic aneurysm …

M Wei, X Wang, Y Song, D Zhu, D Qi, S Jiao… - Frontiers in …, 2021 - frontiersin.org
Objective: Neutrophil infiltration plays an important role in the initiation and development of
abdominal aortic aneurysm (AAA). Recent studies suggested that neutrophils could release …

AAAKB: A manually curated database for tracking and predicting genes of Abdominal aortic aneurysm (AAA)

D Yao, S Mei, W Tang, X Xu, Q Lu, Z Shi - PLoS One, 2023 - journals.plos.org
Abdominal aortic aneurysm (AAA), an extremely dangerous vascular disease with high
mortality, causes massive internal bleeding due to aneurysm rupture. To boost the research …

Computed Tomography Angiography Markers and Intraluminal Thrombus Morphology as Predictors of Abdominal Aortic Aneurysm Rupture

EM Arbănași, AV Mureșan, CM Coșarcă… - International Journal of …, 2022 - mdpi.com
Background: Abdominal aortic aneurysm (AAA) is a complex vascular disease characterized
by progressive and irreversible local dilatation of the aortic wall. Currently, the indication for …

Circ_0092291 attenuates angiotensin II–induced cell damages in human aortic vascular smooth muscle cells via mediating the miR-626/COL4A1 signal axis

M Ma, X Yang, F Han, H Wang - Journal of physiology and biochemistry, 2022 - Springer
Abdominal aortic aneurysm (AAA) is a potentially fatal vascular disease, and the
dysregulated circular RNAs (circRNAs) play key roles in AAA progression. Circ_0092291 …

miRNA Regulatory Networks Associated with Peripheral Vascular Diseases

DP Zalewski, KP Ruszel, A Stępniewski… - Journal of Clinical …, 2022 - mdpi.com
A growing body of evidence indicates a crucial role of miRNA regulatory function in a variety
of mechanisms that contribute to the development of diseases. In our previous work …

Cellular, Molecular and Clinical Aspects of Aortic Aneurysm—Vascular Physiology and Pathophysiology

D Domagała, K Data, H Szyller, M Farzaneh… - Cells, 2024 - mdpi.com
A disturbance of the structure of the aortic wall results in the formation of aortic aneurysm,
which is characterized by a significant bulge on the vessel surface that may have …

[PDF][PDF] Bioinformatics-based identification of lipid-and immune-related biomarkers in abdominal aortic aneurysms

Y Li, R Li, S Guo, Y Li, Y Wang, X Wen, T Lan, K Gong - Heliyon, 2023 - cell.com
Background Abdominal aortic aneurysm (AAA) manifest as a natural inflammatory process
with permanent dilation and terminal rupture. Nevertheless, the pathogenesis of AAA …