Intracranial aneurysms (IAs) linger as a potentially devastating clinical problem. Despite
intense investigation, our understanding of the mechanisms leading to aneurysm …

Cardiovascular diseases (CVD) are the major cause of death in developed countries.
Various risk factors including host genetics and, more importantly, environmental factors …

Thoracic stent-grafts provided by manufacturers were approved in Japan in March 2008,
and their use is now spreading rapidly. Evidence of the efficacy of this treatment in TAA is …

Smoking is an established risk factor for subarachnoid hemorrhage yet the underlying
mechanisms are largely unknown. Recent data has implicated a role of inflammation in the …

Rationale: Histological examination of abdominal aortic aneurysm (AAA) tissues
demonstrates extracellular matrix destruction and infiltration of inflammatory cells. Previous …

Background Screening for abdominal aortic aneurysm (AAA) in selected groups is now
performed in England, the USA and Sweden. Patients with aneurysms over 55 mm in …

Aims Abdominal aortic aneurysm (AAA) is characterized by extensive aortic wall matrix
degradation that contributes to the remodelling and eventual rupture of the arterial wall …

Identifying biomarkers for abdominal aortic aneurysms (AAA) is key to understanding their
pathogenesis, developing novel targeted therapeutics, and possibly improving patients …

Abdominal aortic aneurysm (AAA) is a prevalent and potentially life threatening disease.
Many animal models have been developed to simulate the natural history of the disease or …

Understanding the biology of intracranial aneurysms is a clinical quandary. How these
aneurysms form, progress, and rupture is poorly understood. Evidence indicates that well …