This paper is the forty-fourth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

The number of Americans with opioid use disorder (OUD) has steadily risen over the past 2
decades, now affecting roughly 2.7 million adults. 1 The number of drug overdose deaths …

Background Although use of buprenorphine for treating opioid use disorder increased over
the past decade, buprenorphine utilization remains limited in lower-income and rural areas …

Objective To examine the relative changes in opioid overdose mortality rates between states
that have and have not adopted naloxone co-prescribing laws. Methods We performed a …

Background A limited number of studies have analyzed prescribing among Medicare‐
enrolled adults at risk for opioid overdoses. The objectives of this study were to evaluate …

Background Insurance status may influence quality of opioid analgesic (OA) prescribing
among patients seen by the same clinician. Objective To explore how high-risk OA …

Online Appendix Figures Page 1 Online Appendix Price Sensitivity and Information Barriers
to the Take-up of Naloxone Mireille Jacobson and David Powell Figures Figure A1: Script …

Objectives Efforts to improve low naloxone uptake to mitigate the current opioid crisis have
included coprescribing naloxone with opioid medications and, more recently, expansion …

Background The opioid epidemic is a progressively worsening public health crisis that
continues to impact healthcare system strategies such as overdose reversal and …

Context Older adults are less likely than younger adults to receive naloxone therapy. Given
high rates of prescription opioid use/misuse and increasing illicit opioid use among older …