Abstract Background Glioma stem cells (GSCs) are a subpopulation of stem-like cells that
contribute to glioblastoma (GBM) aggressiveness, recurrence, and resistance to radiation …

Glioblastoma (GBM) is an aggressive brain tumor whose growth is driven by stem cell-like
cells. BMP signaling triggers cell-cycle exit and differentiation of GBM stem cells (GSCs) …

Advances in understanding how cancer cells interact with the immune system allowed the
development of immunotherapeutic strategies, harnessing patients' immune system to fight …

Mesenchymal stem cells (MSC s) are being assessed for ameliorating the severity of graft‐
versus‐host disease, autoimmune conditions, musculoskeletal injuries and cardiovascular …

Tumour‐associated oncogenes induce unscheduled proliferation as well as genomic and
chromosomal instability. According to current models, therapeutic strategies that block …

Precise targeting of genetic lesions alone has been insufficient to extend brain tumor patient
survival. Brain cancer cells are diverse in their genetic, metabolic and microenvironmental …

Cancer cells, stem cells and cancer stem cells have for a long time played a significant role
in the biomedical sciences. Though cancer therapy is more effective than it was a few years …

T-3775440 is an irreversible inhibitor of the chromatin demethylase LSD1, which exerts
antiproliferative effects by disrupting the interaction between LSD1 and GFI1B, a SNAG …

Cancer stem-like cells represent poorly differentiated multipotent tumor-propagating cells
that contribute disproportionately to therapeutic resistance and tumor recurrence …

Tumor cells actively contribute to constructing their own microenvironment during
tumorigenesis and tumor progression. The tumor microenvironment contains multiple types …