[HTML][HTML] DNA methylation and histone modifications as epigenetic regulation in prostate cancer
M Nowacka-Zawisza, E Wiśnik - Oncology reports, 2017 - spandidos-publications.com
Prostate cancer is the second most commonly diagnosed cancer in men in Poland after lung
cancer and the third leading cause of cancer-related mortality after lung and colon cancer …
cancer and the third leading cause of cancer-related mortality after lung and colon cancer …
Epigenetics in breast and prostate cancer
Y Wu, M Sarkissyan, JV Vadgama - Cancer Epigenetics: Risk Assessment …, 2015 - Springer
Most recent investigations into cancer etiology have identified a key role played by
epigenetics. Specifically, aberrant DNA and histone modifications which silence tumor …
epigenetics. Specifically, aberrant DNA and histone modifications which silence tumor …
[HTML][HTML] DNA hypermethylation associated with upregulated gene expression in prostate cancer demonstrates the diversity of epigenetic regulation
I Rauluseviciute, F Drabløs, MB Rye - BMC medical genomics, 2020 - Springer
Abstract Background Prostate cancer (PCa) has the highest incidence rates of cancers in
men in western countries. Unlike several other types of cancer, PCa has few genetic drivers …
men in western countries. Unlike several other types of cancer, PCa has few genetic drivers …
[HTML][HTML] Random forest-based modelling to detect biomarkers for prostate cancer progression
R Toth, H Schiffmann, C Hube-Magg, F Büscheck… - Clinical …, 2019 - Springer
Background The clinical course of prostate cancer (PCa) is highly variable, demanding an
individualized approach to therapy. Overtreatment of indolent PCa cases, which likely do not …
individualized approach to therapy. Overtreatment of indolent PCa cases, which likely do not …
[HTML][HTML] Regulation of epigenetic traits of the glutathione S-transferase P1 gene: from detoxification toward cancer prevention and diagnosis
M Schnekenburger, T Karius… - Frontiers in pharmacology, 2014 - frontiersin.org
Glutathione S-transferases (GSTs) are phase II drug detoxifying enzymes that play an
essential role in the maintenance of cell integrity and protection against DNA damage by …
essential role in the maintenance of cell integrity and protection against DNA damage by …
[HTML][HTML] Integrative Analysis of DNA Methylation and Gene Expression Data Identifies EPAS1 as a Key Regulator of COPD
S Yoo, S Takikawa, P Geraghty, C Argmann… - PLoS …, 2015 - journals.plos.org
Chronic Obstructive Pulmonary Disease (COPD) is a complex disease. Genetic, epigenetic,
and environmental factors are known to contribute to COPD risk and disease progression …
and environmental factors are known to contribute to COPD risk and disease progression …
Development of castration resistant prostate cancer can be predicted by a DNA hypermethylation profile
JC Angulo, G Andrés, N Ashour… - The Journal of …, 2016 - Elsevier
Purpose Detection of DNA hypermethylation has emerged as a novel molecular biomarker
for prostate cancer diagnosis and evaluation of prognosis. We sought to define whether a …
for prostate cancer diagnosis and evaluation of prognosis. We sought to define whether a …
De novo assembly of a haplotype-resolved human genome
The human genome is diploid, and knowledge of the variants on each chromosome is
important for the interpretation of genomic information. Here we report the assembly of a …
important for the interpretation of genomic information. Here we report the assembly of a …
[HTML][HTML] Epigenetically inactivated RASSF1A as a tumor biomarker
RASSF1A, one of the eight isoforms of the RASSF1 gene, is a tumor suppressor gene that
influences tumor initiation and development. In cancer, RASSF1A is frequently inactivated …
influences tumor initiation and development. In cancer, RASSF1A is frequently inactivated …
Tannic acid inhibits proliferation, migration, invasion of prostate cancer and modulates drug metabolizing and antioxidant enzymes
S Karakurt, O Adali - Anti-Cancer Agents in Medicinal …, 2016 - ingentaconnect.com
The aim of this study was to investigate the effects of plant phenolic compound tannic acid
(TA) on proliferative, metastatic, invasive properties of prostate cancer (PCa) cells; PC-3 and …
(TA) on proliferative, metastatic, invasive properties of prostate cancer (PCa) cells; PC-3 and …