The combinatorial pattern of DNA and histone modifications constitutes an epigenetic 'code
'that shapes gene-expression patterns by enabling or restricting the transcriptional potential …

In vertebrates, densely methylated DNA is associated with inactive transcription. Actors in
this process include proteins of the MBD family that can recognize methylated CpGs and …

Maintenance of CG methylation (m CG) patterns is essential for chromatin-mediated
epigenetic regulation of transcription in plants and mammals. However, functional links …

In higher eukaryotes, up to 70% of genes have high levels of nonmethylated
cytosine/guanine base pairs (CpGs) surrounding promoters and gene regulatory units …

DNA methylation is a major epigenetic process that regulates chromatin structure which
causes transcriptional activation or repression of genes in a context-dependent manner. In …

The corepressor BCOR potentiates transcriptional repression by the proto-oncoprotein
BCL6 and suppresses the transcriptional activity of a common mixed-lineage leukemia …

DNA methylation is interpreted by a family of methyl-CpG binding domain (MBD) proteins
that repress transcription through recruitment of corepressors that modify chromatin. To …

Epigenetics refers to a variety of processes that have heritable effects on gene expression
programs without changes in DNA sequence. Key players in epigenetic control are chemical …

Posttranslational modifications of histones are coupled in the regulation of the cellular
processes involving chromatin, such as transcription, replication, repair, and genome …

Methylation of cytosines and adenines in DNA is a widespread epigenetic mark in both
prokaryotes and eukaryotes. In eukaryotes, it has a profound influence on chromatin …