Reactive oxygen species (ROS) and nitric oxide (NO) are produced in all aerobic life forms
under both physiological and adverse conditions. Unregulated ROS/NO generation causes …

This review analyzes the relationship between microvesicles and reactive oxygen species
(ROS). This relationship is bidirectional; on the one hand, the number and content of …

Reactive oxygen species (ROS) and reactive nitrogen species (RNS) play important roles in
regulation of cell survival. In general, moderate levels of ROS/RNS may function as signals …

A constant supply of oxygen is indispensable for cardiac viability and function. However, the
role of oxygen and oxygen-associated processes in the heart is complex, and they and can …

Cell cycle progression is regulated by a wide variety of external factors, amongst them are
growth factors and extracellular matrix factors. During the last decades evidence has been …

The air that we breathe contains nearly 21% oxygen, most of which is utilized by
mitochondria during respiration. While we cannot live without it, it was perceived as a bane …

Regulated production of reactive oxygen species (ROS)/reactive nitrogen species (RNS)
adequately balanced by antioxidant systems is a prerequisite for the participation of these …

Reactive oxygen species (ROS), including superoxide (· O 2−), hydrogen peroxide (H 2 O 2),
and hydroxyl anion (OH-), and reactive nitrogen species, such as nitric oxide (NO) and …

The lung is a highly specialized organ that facilitates uptake of oxygen and release of
carbon dioxide. Due to its unique structure providing enormous surface area to outside …

Metformin, an FDA‐approved antidiabetic drug, has been shown to elongate lifespan in
animal models. Nevertheless, the effects of metformin on human cells remain unclear. Here …