[HTML][HTML] Roadblocks confronting widespread dissemination and deployment of Organs on Chips
Organ on Chip platforms hold significant promise as alternatives to animal models or
traditional cell cultures, both of which poorly recapitulate human pathophysiology and …
traditional cell cultures, both of which poorly recapitulate human pathophysiology and …
Colon-targeted delivery of polyphenols: construction principles, targeting mechanisms and evaluation methods
Y Wang, Z Li, Y Bao, H Cui, J Li, B Song… - Critical Reviews in …, 2023 - Taylor & Francis
Polyphenols have received considerable attention for their promotive effects on colonic
health. However, polyphenols are mostly sensitive to harsh gastrointestinal environments …
health. However, polyphenols are mostly sensitive to harsh gastrointestinal environments …
Toxicokinetic analysis of the highly toxic nerve agent VX in commercially available multi-organ-chips–ways to overcome compound absorption
N Amend, M Koller, C Schmitt, F Worek - Toxicology Letters, 2024 - Elsevier
Organ-on-a-chip technology is considered a next-generation platform in pharmacology and
toxicology. Nevertheless, this novel technology still faces several challenges concerning the …
toxicology. Nevertheless, this novel technology still faces several challenges concerning the …
Interface-driven structural evolution on diltiazem as novel uPAR inhibitors: From in silico design to in vitro evaluation
S Xie, Y Zhou, H Zhu, X Xu, H Zhang, C Yuan… - 2024 - researchsquare.com
The urokinase-type plasminogen activator receptor (uPAR) emerges as a key target for anti-
metastasis owing to its pivotal role in facilitating the invasive and migratory processes of …
metastasis owing to its pivotal role in facilitating the invasive and migratory processes of …