Circulating biomarkers in the diagnosis and management of hepatocellular carcinoma

P Johnson, Q Zhou, DY Dao, YMD Lo - … reviews Gastroenterology & …, 2022 - nature.com
Hepatocellular carcinoma (HCC) is one of the most prevalent and lethal causes of cancer-
related death worldwide. The treatment of HCC remains challenging and is largely …

[HTML][HTML] Multi-omics approaches to disease

Y Hasin, M Seldin, A Lusis - Genome biology, 2017 - Springer
High-throughput technologies have revolutionized medical research. The advent of
genotyping arrays enabled large-scale genome-wide association studies and methods for …

[HTML][HTML] A systematic evaluation of single-cell RNA-sequencing imputation methods

W Hou, Z Ji, H Ji, SC Hicks - Genome biology, 2020 - Springer
Background The rapid development of single-cell RNA-sequencing (scRNA-seq)
technologies has led to the emergence of many methods for removing systematic technical …

Glioblastoma: pathology, molecular mechanisms and markers

K Aldape, G Zadeh, S Mansouri, G Reifenberger… - Acta …, 2015 - Springer
Recent advances in genomic technology have led to a better understanding of key
molecular alterations that underlie glioblastoma (GBM). The current WHO-based …

Prospective evaluation of methylated SEPT9 in plasma for detection of asymptomatic colorectal cancer

TR Church, M Wandell, C Lofton-Day, SJ Mongin… - Gut, 2014 - gut.bmj.com
Background As screening methods for colorectal cancer (CRC) are limited by uptake and
adherence, further options are sought. A blood test might increase both, but none has yet …

Glioma CpG island methylator phenotype (G-CIMP): biological and clinical implications

TM Malta, CF de Souza, TS Sabedot, TC Silva… - Neuro …, 2018 - academic.oup.com
Gliomas are a heterogeneous group of brain tumors with distinct biological and clinical
properties. Despite advances in surgical techniques and clinical regimens, treatment of high …

[HTML][HTML] Genomic instability in human cancer: Molecular insights and opportunities for therapeutic attack and prevention through diet and nutrition

LR Ferguson, H Chen, AR Collins, M Connell… - Seminars in cancer …, 2015 - Elsevier
Genomic instability can initiate cancer, augment progression, and influence the overall
prognosis of the affected patient. Genomic instability arises from many different pathways …

Assessing the impact of low level laser therapy (LLLT) on biological systems: a review

RA Mussttaf, DFL Jenkins, AN Jha - International journal of …, 2019 - Taylor & Francis
Purpose: Low level laser therapy (LLLT) in the visible to near infrared spectral band (390–
1100 nm) is absorption of laser light at the electronic level, without generation of heat. It may …

Curcumin use in pulmonary diseases: State of the art and future perspectives

D Lelli, A Sahebkar, TP Johnston, C Pedone - Pharmacological research, 2017 - Elsevier
Curcumin (diferuloylmethane) is a yellow pigment present in the spice turmeric (Curcuma
longa). It has been used for centuries in Ayurveda (Indian traditional medicine) for the …

Gene silencing in cancer in association with promoter hypermethylation

JG Herman, SB Baylin - New England Journal of Medicine, 2003 - Mass Medical Soc
This article reviews the mechanisms of gene silencing in cancer and clinical applications of
this phenomenon. The silencing of genes, especially tumor-suppressor genes, is a key …