Total volatile basic nitrogen and trimethylamine in muscle foods: Potential formation pathways and effects on human health
The use of total volatile basic nitrogen (TVB‐N) as a quality parameter for fish is rapidly
growing to include other types of meat. Investigations of meat quality have recently focused …
growing to include other types of meat. Investigations of meat quality have recently focused …
Can diet modulate trimethylamine N-oxide (TMAO) production? What do we know so far?
KS Coutinho-Wolino, LFM de F. Cardozo… - European journal of …, 2021 - Springer
Abstract Background Trimethylamine N-oxide (TMAO) is a metabolite that has attracted
attention due to its positive association with several chronic non-communicable diseases …
attention due to its positive association with several chronic non-communicable diseases …
[HTML][HTML] Aorta-and liver-generated TMAO enhances trained immunity for increased inflammation via ER stress/mitochondrial ROS/glycolysis pathways
We determined whether gut microbiota-produced trimethylamine (TMA) is oxidized into
trimethylamine N-oxide (TMAO) in nonliver tissues and whether TMAO promotes …
trimethylamine N-oxide (TMAO) in nonliver tissues and whether TMAO promotes …
Trimethylamine N-oxide exacerbates renal inflammation and fibrosis in rats with diabetic kidney disease
Q Fang, B Zheng, N Liu, J Liu, W Liu, X Huang… - Frontiers in …, 2021 - frontiersin.org
The gut microbiota plays a pivotal role in the onset and development of diabetes and its
complications. Trimethylamine N-oxide (TMAO), a gut microbiota-dependent metabolite of …
complications. Trimethylamine N-oxide (TMAO), a gut microbiota-dependent metabolite of …
Gut microbiota and chronic kidney disease: evidences and mechanisms that mediate a new communication in the gastrointestinal-renal axis
NL Rukavina Mikusic, NM Kouyoumdzian… - Pflügers Archiv-European …, 2020 - Springer
Chronic kidney disease (CKD) represents a growing public health problem associated with
loss of kidney function and cardiovascular disease (CVD), the main leading cause of …
loss of kidney function and cardiovascular disease (CVD), the main leading cause of …
The human microbiome in chronic kidney disease: a double-edged sword
Chronic kidney disease (CKD) is an increasing global health burden. Current treatments for
CKD include therapeutics to target factors that contribute to CKD progression, including …
CKD include therapeutics to target factors that contribute to CKD progression, including …
Uraemic solutes as therapeutic targets in CKD-associated cardiovascular disease
JD Ravid, MH Kamel, VC Chitalia - Nature Reviews Nephrology, 2021 - nature.com
Chronic kidney disease (CKD) is characterized by the retention of a myriad of solutes termed
uraemic (or uremic) toxins, which inflict damage to several organs, including the …
uraemic (or uremic) toxins, which inflict damage to several organs, including the …
[PDF][PDF] Link between gut microbiota dysbiosis and chronic kidney disease.
During chronic kidney disease (CKD), typical alterations in the gut microbiota are observed.
The kidney no longer plays the role of the main excretory organ as this function is performed …
The kidney no longer plays the role of the main excretory organ as this function is performed …
Longitudinal plasma measures of trimethylamine N‐oxide and risk of atherosclerotic cardiovascular disease events in community‐based older adults
Background Trimethylamine N‐oxide (TMAO) is a gut microbiota‐dependent metabolite of
dietary choline, L‐carnitine, and phosphatidylcholine‐rich foods. On the basis of …
dietary choline, L‐carnitine, and phosphatidylcholine‐rich foods. On the basis of …
Blood–brain barrier and gut barrier dysfunction in chronic kidney disease with a focus on circulating biomarkers and tight junction proteins
L Hernandez, LJ Ward, S Arefin, T Ebert… - Scientific reports, 2022 - nature.com
Kidney failure and associated uraemia have implications for the cardiovascular system,
brain, and blood–brain barrier (BBB). We aim to examine BBB disruption, by assessing brain …
brain, and blood–brain barrier (BBB). We aim to examine BBB disruption, by assessing brain …