A great challenge in neuroscience is understanding how activity in the brain gives rise to
behavior. The zebrafish is an ideal vertebrate model to address this challenge, thanks to the …

Locomotor behaviors are critical for survival and enable animals to navigate their
environment, find food and evade predators. The circuits in the brain and spinal cord that …

The flexibility of motor actions is ingrained in the diversity of neurons and how they are
organized into functional circuit modules, yet our knowledge of the molecular underpinning …

The flexibility of locomotor movements requires an accurate control of their start, duration,
and speed. How brainstem circuits encode and convey these locomotor parameters remains …

Reciprocal activation of flexor and extensor muscles constitutes the fundamental mechanism
that tetrapod vertebrates use for locomotion and limb-driven reflex behaviors. This aspect of …

Spinal circuits generate locomotion with variable speed as circumstances demand. These
circuits have been assumed to convey equal and uniform excitation to all motoneurons …

The classic'size principle'of motor control describes how increasingly forceful movements
arise by the recruitment of motoneurons of progressively larger size and force output into the …

In vertebrates, spinal circuits drive rhythmic firing in motoneurons in the appropriate
sequence to produce locomotor movements. These circuits become active early during …

Locomotion is a complex motor task generated by spinal circuits driving motoneurons in a
precise sequence to control the timing and vigor of movements, but the underlying circuit …

Vertebrate movement is orchestrated by spinal inter-and motor neurons that, together with
sensory and cognitive input, produce dynamic motor behaviors. These behaviors vary from …