[HTML][HTML] Exosome-mediated immunosuppression in tumor microenvironments

QH Xie, JQ Zheng, JY Ding, YF Wu, L Liu, ZL Yu… - Cells, 2022 - mdpi.com
Exosomes are membranous structures secreted by nearly all cell types. As critical
messengers for intercellular communication, exosomes deliver bioactive cargoes to …

[HTML][HTML] Exosomes as smart drug delivery vehicles for cancer immunotherapy

H Zhang, S Wang, M Sun, Y Cui, J Xing… - Frontiers in …, 2023 - frontiersin.org
Exosomes (Exos) as drug delivery vehicles have been widely used for cancer
immunotherapy owing to their good biocompatibility, low toxicity, and low immunogenicity …

[HTML][HTML] Tumor extracellular vesicles mediate anti-PD-L1 therapy resistance by decoying anti-PD-L1

J Chen, J Yang, W Wang, D Guo, C Zhang… - Cellular & Molecular …, 2022 - nature.com
Abstract PD-L1+ tumor-derived extracellular vesicles (TEVs) cause systemic
immunosuppression and possibly resistance to anti-PD-L1 antibody (αPD-L1) blockade …

[HTML][HTML] Emerging role of extracellular vesicles and cellular communication in metastasis

A Forder, CY Hsing, J Trejo Vazquez, C Garnis - Cells, 2021 - mdpi.com
Communication between cancer cells and the surrounding stromal cells of the tumor
microenvironment (TME) plays a key role in promoting metastasis, which is the major cause …

[HTML][HTML] Tumor-derived extracellular vesicles promote activation of carcinoma-associated fibroblasts and facilitate invasion and metastasis of ovarian cancer by …

Y Cui, D Wang, M Xie - Frontiers in cell and developmental biology, 2021 - ncbi.nlm.nih.gov
Ovarian cancer (OC) is a lethal gynecological malignancy. Extracellular vesicles (EVs) are
crucial media in cell-to-cell communication by carrying microRNAs (miRs). The current study …

[HTML][HTML] The dual action of glioma-derived exosomes on neuronal activity: synchronization and disruption of synchrony

R Spelat, N Jihua, CA Sánchez Triviño, S Pifferi… - Cell Death & …, 2022 - nature.com
Seizures represent a frequent symptom in gliomas and significantly impact patient morbidity
and quality of life. Although the pathogenesis of tumor-related seizures is not fully …

[HTML][HTML] Extracellular vesicles in the tumor immune microenvironment

P Hou, H Chen - Cancer letters, 2021 - Elsevier
Extracellular vesicles (EVs) have gained significant attention in recent decades as major
mediators of intercellular communication that are involved in various essential physiological …

[HTML][HTML] Extracellular vesicles mediate biological information delivery: A double-edged sword in cardiac remodeling after myocardial infarction

P Cheng, X Wang, Q Liu, T Yang, H Qu… - Frontiers in …, 2023 - frontiersin.org
Acute myocardial infarction (AMI) is a severe ischemic disease with high morbidity and
mortality worldwide. Maladaptive cardiac remodeling is a series of abnormalities in cardiac …

[HTML][HTML] Lung cancer stem cells—origin, diagnostic techniques and perspective for therapies

A Raniszewska, I Kwiecień, E Rutkowska, P Rzepecki… - Cancers, 2021 - mdpi.com
Simple Summary Lung cancer is still a serious oncological problem worldwide. Thus, the
biology of this cancer is of interest. Cancer stem cells (CSCs) are involved in tumor initiation …

[HTML][HTML] Mechanism of tumor‑derived extracellular vesicles in regulating renal cell carcinoma progression by the delivery of MALAT1

C Jin, L Shi, K Li, W Liu, Y Qiu, Y Zhao… - Oncology …, 2021 - spandidos-publications.com
Renal cell carcinoma (RCC) is a major healthcare burden globally. Tumor‑derived
extracellular vesicles (EVs) contribute to the formation of a pro‑metastatic microenvironment …