Abstract The 2020 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice
Guideline on the Evaluation and Management of Candidates for Kidney Transplantation is …

The C3 glomerulopathies are a group of rare kidney diseases characterized by complement
dysregulation occurring in the fluid phase and in the glomerular microenvironment, which …

Monoclonal gammopathy of renal significance (MGRS) regroups all renal disorders caused
by a monoclonal immunoglobulin (MIg) secreted by a nonmalignant B-cell clone. By …

Most glomerulonephritides, even the more common types, are rare diseases. They are
nevertheless important since they frequently affect young people, often cannot be cured, and …

Recurrent glomerulonephritis (GN) is an important cause of kidney allograft failure,
particularly in younger recipients. Approximately 15% of death-censored graft failures are …

Monoclonal immunoglobulins (MIg) may play a causal role in C3 glomerulopathy (C3G) by
impairing regulation of the alternative pathway of complement. Ninety-five patients with C3G …

The prevalence, pathogenesis, predictors, and natural course of patients with recurrent
glomerulonephritis (GN) occurring after kidney transplantation remains incompletely …

Abstract C3 glomerulopathy (C3G) describes a pathologic pattern of injury diagnosed by
renal biopsy. It is characterized by the dominant deposition of the third component of …

Complement defects are associated with an enhanced risk of a broad spectrum of infectious
as well as systemic or local inflammatory and thrombotic disorders. Inherited complement …

Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …