In recent years, a number of studies focused on the role of epigenetics, including DNA
methylation, in spermatogenesis and male infertility. We aimed to provide an overview of the …

Male infertility is a complex condition with a strong genetic and epigenetic background. This
review discusses the importance of genetic and epigenetic factors in the pathophysiology of …

Male infertility is an increasing and serious medical concern, though the mechanism
remains poorly understood. Impaired male reproductive function affects approximately half …

Background Spermatogenesis‐associated (SPATA) family of genes plays important roles in
spermatogenesis, sperm maturation or fertilization. The knockout studies in mice have …

The effects of ambient fine particles on male reproductive health have raised widespread
concern. The particular underlying mechanisms of the damage remain largely unclear and …

Environmental variation can influence the reproductive success of species managed under
human care and in the wild, yet the mechanisms underlying this phenomenon remain …

Smoking has been linked to male infertility by affecting the sperm epigenome and genome.
In this study, we aimed to determine possible changes in the transcript levels of PGAM5 (the …

Mammalian E3 ubiquitin ligases have emerged in recent years as critical regulators of
cellular homeostasis due to their roles in targeting substrate proteins for ubiquitination and …

Background Spermatogenesis is a highly regulated and complex process in which DNA
methylation plays a crucial role. This study aimed to explore the differential methylation …

Infertility is a heterogeneous phenotype, and for many couples, the causes of fertility
problems remain unknown. One understudied hypothesis is that allelic interactions between …