[PDF][PDF] Essential Role of Endothelial Smad4 in

WL Yang, X Cheng, N Mao, X Yang - Citeseer
MATERIALS AND METHODS Mouse strains. Mice carrying conditional Smad4 alleles
(Smad4Co/Co)(49) were bred with Tie2-Cre transgenic mice, in which expression of Cre …

The role of time in biological systems: a computational analysis ranging from molecular dynamics to biological network simulations.

A Masiero - 2015 - research.unipd.it
Time is the main character of this thesis, and it has been used in many ways. Starting from
molecular dynamics simulations to biological networks, time has been analysed under …

[HTML][HTML] Von Hippel-Lindau gene expression on the human fallopian tube epithelium during the menstrual cycle

YY Lu, WJ Zhu, BG Xie - Molecular Medicine Reports, 2015 - spandidos-publications.com
Abstract The Von Hippel-Lindau gene (VHL) is a tumor suppressor gene, which is widely
expressed in kidney, lung, breast, ovary, and cervix. VHL gene mutations can induce VHL …

Der Einfluss von Chemotherapeutika mit Hypoxie-induzierbarer Faktor (HIF)-modulierendem Potential sowie eines Verlustes des HIF-Regulators von Hippel-Lindau …

S Trojandt - 2015 - openscience.ub.uni-mainz.de
Der Transkriptionsfaktor Hypoxie-induzierbarer Faktor (HIF) gibt dem Organismus die
Möglichkeit, sich auf zellulärer Ebene an unterschiedliche Sauerstoffverhältnisse …

VHL and HIF in Clear Cell Renal Cell Carcinoma: Molecular Abnormalities and Potential Clinical Applications

L Gossage - Renal Cell Carcinoma: Molecular Targets and Clinical …, 2015 - Springer
Biallelic inactivation of the von Hippel-Lindau (VHL) gene occurs in the majority of sporadic
clear cell renal cell carcinomas (ccRCCs) due to a combination of somatic mutations, VHL …

[引用][C] The von Hippel-Lindau tumor suppressor regulates E2F1

DA Mans, BG Weijts, JS Vermaat, LG Daenen… - Novel functions of the von Hippel …

Die Interaktion von VHL und PTEN bei der Tumorinitiation und Progression

R Keppler - 2013 - openscience.ub.uni-mainz.de
Das VHL-Syndrom umfasst Erkrankungen, die mit einem Funktionsverlust von VHL
einhergehen. Das Tumorspektrum umfasst retinale und zerebrale Hämangioblastome …

Role of Nek1 in VHL and cell cycle regulation

M Patil - 2013 - search.proquest.com
Nek1 is the member of NIMA (Never in mitosis gene A) related protein kinase family that is
widely expressed in mammals. Nek1 is an essential protein because loss of function in Nek1 …

[图书][B] Identification of Novel HIF1A Target Genes That Regulate Tumor Progression and Metastasis

DL Peacock - 2013 - search.proquest.com
Hypoxia is a hallmark of most solid tumors. In response to hypoxic stress tumor cells adapt
by regulating survival, metabolism and angiogenesis. The heterodimeric Hypoxia-Inducible …

[PDF][PDF] Analysis of an fih mutation in the zebrafish

EC Judson - 2012 - etheses.whiterose.ac.uk
Hypoxic signaling is involved in homeostatic and developmental angiogenic and
neurogenic proliferation and differentiation as well as modulating many disease processes …