Aging involves a diverse set of biological changes accumulating over time that leads to
increased risk of morbidity and mortality. Epigenetic clocks are now widely used to quantify …

DNA methylation data have become a valuable source of information for biomarker
development, because, unlike static genetic risk estimates, DNA methylation varies …

Epigenetic clocks comprise a set of CpG sites whose DNA methylation levels measure
subject age. These clocks are acknowledged as a highly accurate molecular correlate of …

Epigenetic clocks are widely used aging biomarkers calculated from DNA methylation data,
but this data can be surprisingly unreliable. Here we show that technical noise produces …

Background Biological aging estimators derived from DNA methylation data are heritable
and correlate with morbidity and mortality. Consequently, identification of genetic and …

Advanced age is the main common risk factor for cancer, cardiovascular disease and
neurodegeneration. Yet, more is known about the molecular basis of any of these groups of …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with an estimated
heritability between 40 and 50%. DNA methylation patterns can serve as proxies of (past) …

Background Epigenetic clocks can track both chronological age (cAge) and biological age
(bAge). The latter is typically defined by physiological biomarkers and risk of adverse health …

Simple Summary Research on plant epigenetics aims to understand how endogenous,
biotic, and abiotic factors regulate plant development and growth independent of changes in …

An improved understanding of etiological mechanisms in Parkinson's disease (PD) is
urgently needed because the number of affected individuals is projected to increase rapidly …