Relationships among smoking, oxidative stress, inflammation, macromolecular damage, and cancer
Smoking is a major risk factor for a variety of diseases, including cancer and immune-
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …
mediated inflammatory diseases. Tobacco smoke contains a mixture of chemicals, including …
The roles of DNA, RNA and histone methylation in ageing and cancer
Chromatin is a macromolecular complex predominantly comprising DNA, histone proteins
and RNA. The methylation of chromatin components is highly conserved as it helps …
and RNA. The methylation of chromatin components is highly conserved as it helps …
DNA hypermethylation in disease: mechanisms and clinical relevance
M Ehrlich - Epigenetics, 2019 - Taylor & Francis
Increasing numbers of studies implicate abnormal DNA methylation in cancer and many non-
malignant diseases. This is consistent with numerous findings about differentiation …
malignant diseases. This is consistent with numerous findings about differentiation …
Molecular tumour boards—current and future considerations for precision oncology
AM Tsimberidou, M Kahle, HH Vo, MA Baysal… - Nature Reviews …, 2023 - nature.com
Over the past 15 years, rapid progress has been made in developmental therapeutics,
especially regarding the use of matched targeted therapies against specific oncogenic …
especially regarding the use of matched targeted therapies against specific oncogenic …
[HTML][HTML] Polyphenols as potent epigenetics agents for cancer
Human diseases such as cancer can be caused by aberrant epigenetic regulation.
Polyphenols play a major role in mammalian epigenome regulation through mechanisms …
Polyphenols play a major role in mammalian epigenome regulation through mechanisms …
Recent advances and emerging trends in cancer biomarker detection technologies
Cancer is a major global health burden and poor survival rates can be attributed to lack of
early diagnosis and limited access to timely and standard treatments. Significant progress …
early diagnosis and limited access to timely and standard treatments. Significant progress …
Identification of pyroptosis-related subtypes, the development of a prognosis model, and characterization of tumor microenvironment infiltration in colorectal cancer
W Song, J Ren, R Xiang, C Kong, T Fu - Oncoimmunology, 2021 - Taylor & Francis
Pyroptosis is a newly discovered programmed cell death that is associated with tumor
progression, prognosis, and treatment response. However, the potential roles of pyroptosis …
progression, prognosis, and treatment response. However, the potential roles of pyroptosis …
[HTML][HTML] KIAA1429 contributes to liver cancer progression through N6-methyladenosine-dependent post-transcriptional modification of GATA3
T Lan, H Li, D Zhang, L Xu, H Liu, X Hao, X Yan… - Molecular cancer, 2019 - Springer
Abstract Background N6-methyladenosine (m6A) modification, the most abundant internal
methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing. As the …
methylation of eukaryotic RNA transcripts, is critically implicated in RNA processing. As the …
[HTML][HTML] Properties and behavior of carbon nanomaterials when interfacing neuronal cells: How far have we come?
In the last two decades, an increasing amount of studies have investigated the use of
components based on carbon-(nano) materials in the engineering of neural interfaces, to …
components based on carbon-(nano) materials in the engineering of neural interfaces, to …
[HTML][HTML] The roles of human DNA methyltransferases and their isoforms in shaping the epigenome
A DNA sequence is the hard copy of the human genome and it is a driving force in
determining the physiological processes in an organism. Concurrently, the chemical …
determining the physiological processes in an organism. Concurrently, the chemical …