Chromatin remodeling and leukemia: new therapeutic paradigms
RL Redner, J Wang, JM Liu - … Journal of the American Society of …, 1999 - ashpublications.org
LOCAL REMODELING OF chromatin is a key step in the transcriptional activation of genes.
Dynamic changes in the nucleosomal packaging of DNA must occur to allow transcriptional …
Dynamic changes in the nucleosomal packaging of DNA must occur to allow transcriptional …
Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS–M
C Plass, H Shibata, I Kalcheva, L Mullins… - Nature …, 1996 - nature.com
Normal mammalian development requires a diploid combination of both haploid parental
genomes1. Uniparental disomy for certain segments of specific chromosomes results in …
genomes1. Uniparental disomy for certain segments of specific chromosomes results in …
Early-life exposure to severe famine is associated with higher methylation level in the IGF2 gene and higher total cholesterol in late adulthood: the Genomic Research …
Objective To evaluate the association of early-life exposure to the Chinese Great Famine
(1959–1961) with DNA methylation in IGF2 and its subsequent influence on blood lipid …
(1959–1961) with DNA methylation in IGF2 and its subsequent influence on blood lipid …
Delineating the epigenetic regulation of heat and drought response in plants
Being sessile in nature, plants cannot overlook the incursion of unfavorable environmental
conditions, including heat and drought. Heat and drought severely affect plant growth …
conditions, including heat and drought. Heat and drought severely affect plant growth …
Dnmt3 and G9a Cooperate for Tissue-specific Development in Zebrafish 2
Although DNA methylation is critical for proper embryonic and tissue-specific development,
how different DNA methyltransferases affect tissue-specific development and their targets …
how different DNA methyltransferases affect tissue-specific development and their targets …
[HTML][HTML] Epigenetic control of the genome—lessons from genomic imprinting
BT Adalsteinsson, AC Ferguson-Smith - Genes, 2014 - mdpi.com
Epigenetic mechanisms modulate genome function by writing, reading and erasing
chromatin structural features. These have an impact on gene expression, contributing to the …
chromatin structural features. These have an impact on gene expression, contributing to the …
Characterization of the stability of recombinant protein production in the GS‐NS0 expression system
LM Barnes, CM Bentley… - Biotechnology and …, 2001 - Wiley Online Library
The GS‐NS0 system is an important mammalian expression system used largely within
industry for the high‐level expression of recombinant proteins for therapeutic use. It is …
industry for the high‐level expression of recombinant proteins for therapeutic use. It is …
Promoter methylation status of E-cadherin, hMLH1, and p16 genes in nonneoplastic gastric epithelia
T Waki, G Tamura, T Tsuchiya, K Sato… - The American journal of …, 2002 - Elsevier
Silencing of tumor suppressor and tumor-related genes by hypermethylation at promoter
CpG islands is one of the major events in human tumorigenesis. Promoter methylation is …
CpG islands is one of the major events in human tumorigenesis. Promoter methylation is …
Epigenetics in social insects: a new direction for understanding the evolution of castes
Epigenetic modifications to DNA, such as DNA methylation, can expand a genome's
regulatory flexibility, and thus may contribute to the evolution of phenotypic plasticity. Recent …
regulatory flexibility, and thus may contribute to the evolution of phenotypic plasticity. Recent …
Pan-cancer analysis of immune complement signature C3/C5/C3AR1/C5AR1 in association with tumor immune evasion and therapy resistance
B Lawal, SH Tseng, JO Olugbodi, S Iamsaard… - Cancers, 2021 - mdpi.com
Simple Summary We used multi-omics approaches to evaluate the association of
complement signature C3/C5/C3AR1/C5AR1 with tumor immune phenotypes and prognosis …
complement signature C3/C5/C3AR1/C5AR1 with tumor immune phenotypes and prognosis …