Atopic dermatitis (AD) is a complex skin disease frequently associated with other diseases of
the atopic diathesis. Recent evidence supports the concept that AD can also recognize other …

Atopic dermatitis (AD) is a paradigmatic chronic inflammatory skin disease characterized by
a complex pathophysiology and a wide spectrum of the clinical phenotype. Despite this high …

Background Despite unmet need, 15 years have passed since a topical therapy with a new
mechanism of action for atopic dermatitis (AD) has been approved. Janus kinase (JAK) …

Type 2 immunity evolved to combat helminth infections by orchestrating a combined
protective response of innate and adaptive immune cells and promotion of parasitic worm …

Na última década o conhecimento sobre a etiopatogenia da alergia alimentar (AA) avançou
muito. A identificaçao de novas formas clínicas de apresentaçao, aliada à aquisiçao de …

Atopic dermatitis (AD) or atopic eczema is the common inflammatory skin disorder, the
prevalence of which has considerably increased during the last 30 years. It affects 15 …

Fc-fusion proteins are composed of Fc region of IgG antibody (Hinge-CH2-CH3) and a
desired linked protein. Fc region of Fc-fusion proteins can bind to neonatal Fc receptor …

Psoriasis and atopic dermatitis are common, chronic inflammatory skin diseases. We
discuss several aspects of these disorders, including: risk factors; incidence and prevalence; …

Highlights•Interleukin (IL)-6/STAT3/ERBIN pathway retrains human Th2 cells.•IFNγ, but not
IL-12, is a negative regulator of human Th2 cell development.•STAT6 is a key driver of Th2 …

Background The skin of atopic dermatitis (AD) patients presents a significant dysbalance of
the microbiome with a high colonization by Staphylococcus aureus (S. aureus), which …