Methylation‐specific PCR (MSP) is a simple, quick and cost‐effective method to analyze the
DNA methylation status of virtually any group of CpG sites within a CpG island. The …

Over the past five years, denaturing high-performance liquid chromatography (DHPLC) has
emerged as one of the most versatile technologies for the analysis of genetic variations. With …

Standard methods used for genomic methylation analysis allow the detection of complete
absence of either methylated or non-methylated alleles but are usually unable to detect …

As global arid conditions worsen and groundwater resources diminish, drought stress has
emerged as a critical impediment to plant growth and development globally, notably causing …

Several biological phenomena depend on differential methylation of chromosomal strands.
While understanding the role of these processes requires information on allele-specific …

Background: DNA methylation analysis currently requires complex multistep procedures
based on bisulfite conversion of unmethylated cytosines or on methylation-sensitive …

We describe a young woman with Prader–Willi syndrome (PWS) due to a mosaic imprinting
defect. Three independent assays revealed a reduced proportion of nonmethylated SNURF …

Aberrant promoter hypermethylation of CpG dinucleotides is a frequent and significant
mechanism of tumor suppressor gene (TSG) silencing in cancer. As increasing numbers of …

The bisulfite genomic sequencing method is one of the most widely used techniques for
methylation analysis in heterogeneous unbiased PCR, amplifying for both methylated and …

摘要DNA 甲基化一直是表观遗传学领域研究的重点之一. 研究表明, DNA
甲基化与胚胎发育以及肿瘤和疾病的发生, 发展密切相关, 因此, DNA 甲基化检测具有重要意义 …