The kynurenine pathway: a finger in every pie
J Savitz - Molecular psychiatry, 2020 - nature.com
The kynurenine pathway (KP) plays a critical role in generating cellular energy in the form of
nicotinamide adenine dinucleotide (NAD+). Because energy requirements are substantially …
nicotinamide adenine dinucleotide (NAD+). Because energy requirements are substantially …
[HTML][HTML] Chronic stress and oxidative stress as common factors of the pathogenesis of depression and Alzheimer's disease: The role of antioxidants in prevention and …
G Juszczyk, J Mikulska, K Kasperek, D Pietrzak… - Antioxidants, 2021 - mdpi.com
There is a growing body of scientific research showing the link between depression and
dementia in Alzheimer's disease (AD). The chronic stress contributes to the formation of …
dementia in Alzheimer's disease (AD). The chronic stress contributes to the formation of …
[HTML][HTML] High cortisol and the risk of dementia and Alzheimer's disease: a review of the literature
Introduction: Cortisol effects on the brain are exerted through two distinct receptors, inducing
complex and even opposite effects on the cerebral structures implicated in the various …
complex and even opposite effects on the cerebral structures implicated in the various …
Depression in neurodegenerative diseases: Common mechanisms and current treatment options
CPC Galts, LEB Bettio, DC Jewett, CC Yang… - Neuroscience & …, 2019 - Elsevier
Major depressive disorder (MDD) is a highly prevalent psychiatric disorder and a major
cause of disability worldwide. This neurological condition is commonly associated with …
cause of disability worldwide. This neurological condition is commonly associated with …
Depression, dementia and immune dysregulation
S Hayley, AM Hakim, PR Albert - Brain, 2021 - academic.oup.com
Major depression is a prevalent illness that increases the risk of several neurological
conditions. These include stroke, cardiovascular disease, and dementia including …
conditions. These include stroke, cardiovascular disease, and dementia including …
Adult hippocampal neurogenesis in major depressive disorder and Alzheimer's disease
T Berger, H Lee, AH Young, D Aarsland… - Trends in molecular …, 2020 - cell.com
Depression and dementia are major public health problems. Major depressive disorder
(MDD) and Alzheimer's disease (AD) reciprocally elevate the risk for one another. No …
(MDD) and Alzheimer's disease (AD) reciprocally elevate the risk for one another. No …
Microbiota from Alzheimer's patients induce deficits in cognition and hippocampal neurogenesis
S Grabrucker, M Marizzoni, E Silajdžić, N Lopizzo… - Brain, 2023 - academic.oup.com
Alzheimer's disease is a complex neurodegenerative disorder leading to a decline in
cognitive function and mental health. Recent research has positioned the gut microbiota as …
cognitive function and mental health. Recent research has positioned the gut microbiota as …
[HTML][HTML] The relationship between stress and Alzheimer's disease
NJ Justice - Neurobiology of stress, 2018 - Elsevier
Stress is critically involved in the development and progression of disease. From the stress
of undergoing treatments to facing your own mortality, the physiological processes that …
of undergoing treatments to facing your own mortality, the physiological processes that …
A systematic review of yoga for major depressive disorder
Background The purpose of this review was to investigate the efficacy and safety of yoga
interventions in treating patients with major depressive disorder. Methods MEDLINE …
interventions in treating patients with major depressive disorder. Methods MEDLINE …
[HTML][HTML] Pathways connecting late-life depression and dementia
C Linnemann, UE Lang - Frontiers in pharmacology, 2020 - frontiersin.org
Late-life depression is associated with significant cognitive impairment. Meta-analyses
showed that depression is associated with an increased risk for Alzheimer's disease (AD) …
showed that depression is associated with an increased risk for Alzheimer's disease (AD) …