[HTML][HTML] Melatonin and multiple sclerosis: Antioxidant, anti-inflammatory and immunomodulator mechanism of action

A Muñoz-Jurado, BM Escribano… - …, 2022 - Springer
Background Melatonin is an indole hormone secreted primarily by the pineal gland that
showing anti-oxidant, anti-inflammatory and anti-apoptotic capacity. It can play an important …

[HTML][HTML] Importance of melatonin in assisted reproductive technology and ovarian aging

H Tamura, M Jozaki, M Tanabe, Y Shirafuta… - International journal of …, 2020 - mdpi.com
Melatonin is probably produced in all cells but is only secreted by the pineal gland. The
pineal secretion of melatonin is determined by the light–dark cycle, and it is only released at …

[HTML][HTML] Melatonin alleviates acute sleep deprivation-induced memory loss in mice by suppressing hippocampal ferroptosis

X Wang, Z Wang, J Cao, Y Dong, Y Chen - Frontiers in pharmacology, 2021 - frontiersin.org
Objectives: Memory decline caused by insufficient sleep is a critical public health issues and
currently lacks effective treatments. This study objective was to explore alleviative effect of …

[HTML][HTML] Melatonin: facts, extrapolations and clinical trials

JA Boutin, DJ Kennaway, R Jockers - Biomolecules, 2023 - mdpi.com
Melatonin is a fascinating molecule that has captured the imagination of many scientists
since its discovery in 1958. In recent times, the focus has changed from investigating its …

Efficacy and safety of anti-inflammatory agents in treatment of psychotic disorders–A comprehensive systematic review and meta-analysis

R Jeppesen, RHB Christensen, EMJ Pedersen… - Brain, behavior, and …, 2020 - Elsevier
Objective Antipsychotic effects of immunomodulating drugs have been suggested; however,
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …

[HTML][HTML] Benefits and adverse events of melatonin use in the elderly

L Anghel, L Baroiu, CR Popazu… - Experimental and …, 2022 - spandidos-publications.com
Melatonin is a hormone secreted by the pineal gland in accordance with the circadian
rhythm when the light level decreases. Reduction of melatonin secretion with age may be …

[HTML][HTML] Melatonin ameliorates hepatic ferroptosis in NAFLD by inhibiting ER stress via the MT2/cAMP/PKA/IRE1 signaling pathway

Q Guan, Z Wang, K Hu, J Cao, Y Dong… - International journal of …, 2023 - ncbi.nlm.nih.gov
Ferroptosis, an iron-dependent cell death form, has recently been observed in the
development of non-alcoholic fatty liver disease (NAFLD). Melatonin (Mel) shows potential …

Melatonin restores neutrophil functions and prevents apoptosis amid dysfunctional glutathione redox system

SK NaveenKumar, M Hemshekhar… - Journal of pineal …, 2020 - Wiley Online Library
Melatonin is a chronobiotic hormone, which can regulate human diseases like cancer,
atherosclerosis, respiratory disorders, and microbial infections by regulating redox system …

[HTML][HTML] Dietary fish, fish nutrients, and immune function: A review

CO Mendivil - Frontiers in nutrition, 2021 - frontiersin.org
Dietary habits have a major impact on the development and function of the immune system.
This impact is mediated both by the intrinsic nutritional and biochemical qualities of the diet …

[HTML][HTML] Melatonin inhibits proliferation, migration, and invasion by inducing ROS-mediated apoptosis via suppression of the PI3K/Akt/mTOR signaling pathway in …

K Chen, P Zhu, W Chen, K Luo, XJ Shi… - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Background: Melatonin is an indolic compound mainly secreted by the pineal gland and
plays a vital role in the regulation of circadian rhythms and cancer therapy. However, the …